Evidence map›Paper›PMID 39763721›Full record

ArticlebioRxiv : the preprint server for biology2024

Tonic sound-evoked motility of cochlear outer hair cells in mice with impaired mechanotransduction.

James B Dewey

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

James B DeweyCaruso Department of Otolaryngology - Head & Neck Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.ORCID 0000-0001-5715-9125

Funding

Mechanisms of amplification and nonlinearity in the mouse cochleaR01DC021006 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI James Braden Dewey · 2024 to 2026
$1.2M
Role of tonic outer hair cell motility in cochlear amplificationR21DC019209 · NIDCD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI DEWEY, JAMES BRADEN · 2020 to 2022
$495k
NIDCD NIH HHS R01 DC021006NIDCD NIH HHS R21 DC019209
6 · The paper itself

Abstract

Cochlear outer hair cells (OHCs) transduce sound-induced vibrations of their stereociliary bundles into receptor potentials that drive changes in cell length. While fast, phasic OHC length changes are thought to underlie an amplification process required for sensitive hearing, OHCs also exhibit large tonic length changes. The origins and functional significance of this tonic motility are unclear. Here,

Indexed as

cochlear mechanicsmechanotransductionoptical coherence tomographyouter hair cell motility

Identifiers

PMID39763721
PMCPMC11702648

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.