Evidence map›Paper›PMID 39763719›Full record

ArticlebioRxiv : the preprint server for biology2024

Evolutionary conservation of midline axon guidance activity between

Piyasi Ghosh, Benjamin C Wadsworth, Logan Terry, Timothy A Evans

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Piyasi GhoshDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR 72701.
Benjamin C WadsworthDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR 72701.
Logan TerryDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR 72701.
Timothy A EvansDepartment of Biological Sciences, University of Arkansas, Fayetteville, AR 72701.ORCID 0000-0002-2756-8064

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Functional analysis of the Drosophila axon guidance receptor Robo2R15NS098406 · NINDS · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI EVANS, TIMOTHY A. · 2016 to 2023
$1.3M
NIH HHS P40 OD018537NINDS NIH HHS R15 NS098406
6 · The paper itself

Abstract

The regulation of midline crossing of axons is of fundamental importance for the proper development of nervous system connectivity in bilaterian animals. A number of conserved axon guidance signaling pathways coordinate to attract or repel axons at the nervous system midline to ensure the proper regulation of midline crossing. The attractive Netrin-Frazzled/DCC (Net-Fra) signaling pathway is widely conserved among bilaterians, but it is not clear whether the mechanisms by which Net and Fra promote midline crossing are also conserved. In

Identifiers

PMID39763719
PMCPMC11702761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.