Evidence map›Paper›PMID 39763522›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Transcription Factor RUNX1 Regulates Coagulation Factor XIII-A (

Fabiola Del Carpio-Cano, Natthapol Songdej, Liying Guan, Guangfen Mao, Lawrence E Goldfinger, Jeremy G T Wurtzel, Kiwon Lee, Michele P Lambert, Mortimer Poncz, A Koneti Rao

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Fabiola Del Carpio-Cano
Natthapol Songdej
Liying Guan
Guangfen Mao
Lawrence E GoldfingerORCID 0000-0003-0525-6008
Jeremy G T Wurtzel
Kiwon Lee
Michele P LambertORCID 0000-0003-0439-402X

Funding

Function and regulation of constitutive protein translation in plateletsR01HL159006 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI GOLDFINGER, LAWRENCE E · 2021 to 2024
$1.6M
NHLBI NIH HHS R01 HL159006
6 · The paper itself

Abstract

Background: Germline Aims: To understand RUNX1 regulation of Methods: We performed studies in platelets, HEL cells and human CD34+ cell-derived megakaryocytes including on clot contraction in cells following small inhibitor (si)RNA knockdown (KD) of Results: Platelet Conclusions: RUNX1 regulates platelet-megakaryocyte Essentials: RUNX1 regulates expression of FXIII-A chain (

Identifiers

PMID39763522
PMCPMC11702714

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.