Evidence map›Paper›PMID 39763133›Full record

Trial reportPsycho-oncology2025

A Pilot Randomized Controlled Trial of Families Addressing Cancer Together for Parents With Cancer: Feasibility, Acceptability, and Preliminary Effects.

Zev M Nakamura, Allison M Deal, Justin M Yopp, Alexis C Wardell, Michelle Manning, Phoebe Pak, Anna Cassidy, Laura C Hanson, Ahrang Jung, Mi-Kyung Song and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Zev M NakamuraDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0001-9695-1457
Allison M DealLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Justin M YoppDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Alexis C WardellLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Michelle ManningLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Phoebe PakDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Anna CassidyDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Laura C HansonDivision of Geriatric Medicine & Palliative Care and Hospice Program, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Ahrang JungSchool of Nursing, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-9491-0149
Mi-Kyung SongCenter for Nursing Excellence in Palliative Care, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Carmina G ValleLineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0003-1985-2409
Cole WalkerUniversity of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
Hannah WonDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Eliza M ParkDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.ORCID https://orcid.org/0000-0002-2848-4989
Donald L RosensteinDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

A Psychosocial Intervention to Improve Outcomes for Parents with Advanced CancerK07CA218167 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PARK, ELIZA MYUNG · 2017 to 2021
$884k
Foundation of Hope for Research and Treatment of Mental IllnessNCI NIH HHS 5K07CA218167NCI NIH HHS K07 CA218167
6 · The paper itself

Abstract

objectiveTo evaluate the feasibility, acceptability, and preliminary efficacy of Families Addressing Cancer Together (FACT), a web-based, individually tailored, psychoeducational intervention for parents with cancer to improve illness-related communication with their minor children.

methodsParents with stage I-IV solid tumors who had children ages 3-17 were randomized to 6 weeks of FACT versus waitlist control. Feasibility was assessed by rates of recruitment and retention. Acceptability (primary outcome) was defined a priori as ≥ 75% of FACT participants rating FACT ≥ 12 (on an 18-point study-specific scale), and semi-structured interviews provided additional qualitative acceptability information. Generalized estimating equation methods were used to assess preliminary efficacy for communication self-efficacy, depression, and anxiety; Fisher's exact tests explored differences in individual communication beliefs and behaviors.

resultsForty-eight approached patients enrolled (recruitment rate: 73%), 85% were retained through the post-intervention assessment, and 78% rated FACT as acceptable. In the FACT group compared to control, the modeled improvement in CSES scores from baseline to post-intervention was 9.5 versus 0 points (p = 0.004). FACT participants were more likely to have told their children that they have cancer (83.3% vs. 52.2%, p = 0.03) and felt more prepared to answer their children's questions about cancer (p = 0.02). Groups did not differ in depression or anxiety.

conclusionsFACT was feasible, acceptable, and demonstrated potential to improve parents' communication self-efficacy, beliefs, and behaviors. A large scale randomized controlled trial of FACT is needed to confirm these benefits and evaluate longer-term effects on psychological outcomes for parents with cancer and their children.

Indexed as

AnxietyCommunicationDepressionFeasibility StudiesNeoplasmsParentsSelf EfficacyAdolescentAdultChildChild, PreschoolFemaleHumansInternet-Based InterventionMaleMiddle Agedcancercancer communicationoncologyparenting concernsparents

Identifiers

PMID39763133
PMCPMC11877646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.