Evidence map›Paper›PMID 39762817›Full record

ArticleBMC cancer2025

Breast cancer patterns by age groups in Brazil: insights from population-based registries data.

Jessé Lopes da Silva, Luiz Claudio Santos Thuler, Andréia Cristina de Melo

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessé Lopes da Silva *Division of Clinical Research and Technological Development, Brazilian National Cancer Institute, 37 Andre Cavalcanti Street, 5th floor, Annex Building, 20231050, Rio de Janeiro, Brazil. jesse.silva@inca.gov.br.ORCID http://orcid.org/0000-0002-0790-9917
Luiz Claudio Santos Thuler *Division of Clinical Research and Technological Development, Brazilian National Cancer Institute, 37 Andre Cavalcanti Street, 5th floor, Annex Building, 20231050, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0003-2550-6537
Andréia Cristina de MeloDivision of Clinical Research and Technological Development, Brazilian National Cancer Institute, 37 Andre Cavalcanti Street, 5th floor, Annex Building, 20231050, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-1201-4333

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer (BC) has exhibited varied epidemiological trends based on distinct age categories. This research aimed to explore the incidence and mortality rates of BC within pre-defined age groups in the Brazilian population.

methodsBC incidence trends were assessed from 2010 to 2015 using Brazilian Population-Based Cancer Registries, employing age-standardized ratios and annual average percentage change (AAPC). Hospital-Based Cancer Registries provided clinical and sociodemographic data from 2000 to 2019. Mortality data were obtained from the National Mortality Information System from 2000 to 2020. Three groups were compared: < 40, 40-69, and ≥ 70 years.

resultsFrom 2010 to 2015, 205,966 new BC cases were recorded, with incidence rates of 7.1/100,000 for < 40, 156.5/100,000 for 40-69, and 247.5/100,000 for ≥ 70 years. The < 40 years group exhibited a significant increase in incidence rate (AAPC + 1.6; 95% CI: 1.0 to 2.2; p < 0.001). This age group also showed a higher proportion of black patients (53%, p < 0.001), alcohol consumption (20.5%, p < 0.001), proportion of patients treated at stages ≥ IIB (64.0%, p < 0.001), and a higher likelihood of receiving multiple treatment modalities (60.7%, p < 0.001). The ≥ 70 years group experienced a longer delay exceeding 60 days from diagnosis to treatment onset (54%, p < 0.001), while exhibiting a higher proportion of endocrine therapy utilization (45.3%, p < 0.01). Mortality rates increased across all subgroups, with the < 40 years group showing the most pronounced increase (AAPC + 1.8%; 95% CI: 1.6 to 2.1; p < 0.001).

conclusionThese results highlight marked disparities in BC incidence, mortality rates, clinicopathological and sociodemographic characteristics between women under 40, and those in the 40-69 and ≥ 70 age groups in Brazil.

Indexed as

Breast NeoplasmsRegistriesAdultAgedAged, 80 and overAge FactorsBrazilFemaleHumansIncidenceMiddle AgedAge groupsBreast cancerIncidenceMortality

Identifiers

PMID39762817
PMCPMC11705979

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.