Evidence map›Paper›PMID 39762704›Full record

ArticleBulletin of experimental biology and medicine2024

Activation of Microglia and Astroglia in Unilateral Focal Traumatic Brain Injury in Rats.

E E Genrikhs, M O Shedenkova, D N Voronkov, N K Isaev, E V Stelmashook

Abstract read
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Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

E E GenrikhsResearch Center of Neurology, Moscow, Russia.
M O ShedenkovaLomonosov Moscow State University, Moscow, Russia.
D N VoronkovResearch Center of Neurology, Moscow, Russia.
N K IsaevResearch Center of Neurology, Moscow, Russia.
E V StelmashookResearch Center of Neurology, Moscow, Russia. estelmash@mail.ru.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The number of microglia cells and astrocytes in layer V of the cerebral cortex was estimated on day 7 after damage caused by a unilateral focal traumatic brain injury of the left hemisphere sensorimotor cortex. Quantitative assessment was performed by counting immunocytochemically stained microglia cells (Iba1 marker) and activated astrocytes (GFAP) at different distances from the lesion site. Activation of microglial and astroglial cells was observed not only in the marginal zone of the lesion of the left hemisphere, but also in the intact hemisphere. The data obtained indicate the dissemination of inflammation in focal traumatic brain injury.

Indexed as

AstrocytesBrain Injuries, TraumaticMicrogliaAnimalsCalcium-Binding ProteinsCerebral CortexGlial Fibrillary Acidic ProteinMaleMicrofilament ProteinsRatsRats, WistarAif1 protein, ratCalcium-Binding ProteinsGfap protein, ratGlial Fibrillary Acidic ProteinMicrofilament Proteinsastrocytesinflammationmicrogliatraumatic brain injury

Identifiers

PMID39762704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.