Evidence map›Paper›PMID 39762695›Full record

ArticleBulletin of experimental biology and medicine2024

Changes in the Levels of Short-Chain Acids and Tryptophan Metabolites in Mouse Intestine during Experimental Colitis.

V A Sorokin, T V Grigoryeva, O V Kupriyanova, S A Rumyantsev, A V Shestopalov

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Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

V A SorokinPirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia. sorokin_v_a@mail.ru.
T V GrigoryevaKazan (Volga region) Federal University, Kazan, Russia.
O V KupriyanovaKazan (Volga region) Federal University, Kazan, Russia.
S A RumyantsevPirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia.
A V ShestopalovPirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal balance of the intestinal microbiota is considered to be an essential part of the human body that affects many metabolic processes. However, the exact role of the gut microbiota in metabolism is still not fully understood. To investigate the metabolic role of gut microbiota, the content of short-chain fatty acids and tryptophan metabolites was studied in mice with sodium dextran sulfate-induced colitis. It was found that the production of short-chain fatty acids increased on experimental day 14, but by experimental day 60, they completely disappeared. At the same time, indoles of bacterial origin increased on experimental day 60.

Indexed as

ColitisFatty Acids, VolatileGastrointestinal MicrobiomeTryptophanAnimalsDextran SulfateIndolesIntestinesMaleMiceDextran SulfateFatty Acids, VolatileIndolesTryptophancolitisDSS-induced colitisindolesmicrobiotashort-chain acids

Identifiers

PMID39762695

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.