ArticleNPJ digital medicine2025
Association of real life postural transitions kinematics with fatigue in neurodegenerative and immune diseases.
Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Deployment-Oriented Evaluation of Lightweight IMU-Based Human Activity Recognition: On-Device Efficiency and Streaming Feasibility.Sensors (Basel, Switzerland) · 2026Article
- Bridging the global Parkinson's divide: Technology as a structural solution for equitable and brain health-integrated care.Journal of Parkinson's disease · 2026Review
- Body placement of inertial measurement units differentially affects physical activity assessment accuracy in drug-naïve Parkinson's disease.Scientific reports · 2026Article
- A joint modeling framework for time-to-fatigue prediction with a single wearable sensor biomarker.Scientific reports · 2026Article
- Fatigue-Inducing Protocols in Parkinson's Disease: Implications for Gait Assessment and Rehabilitation: A Systematic Review.Parkinson's disease · 2026Review
- Hybrid mechanistic-machine learning PK/PD models with digital biomarkers: from cage to clinic.Frontiers in pharmacology · 2026Review
- Collection of the digital data from the neurological examination.NPJ digital medicine · 2025Article
- Towards Parkinson's Disease Detection Through Analysis of Everyday Handwriting.Diagnostics (Basel, Switzerland) · 2025Article
- Rotational Power: A New Accelerometer-Derived Metric to Assess Functional Impairment in Multiple Sclerosis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
- Article
- Post-Stroke Fatigue in Patients at 3 Months After Ischemic Stroke: Analysis From the FRAILTY Study.SAGE open nursingArticle
- Article
Corrections and comments
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Authors and funding
22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fatigue is prevalent in immune-mediated inflammatory and neurodegenerative diseases, yet its assessment relies largely on patient-reported outcomes, which capture perception but not fluctuations over time. Wearable sensors, like inertial measurement units (IMUs), offer a way to monitor daily activities and evaluate functional capacity. This study investigates the relationship between sit-to-stand and stand-to-sit transitions and self-reported physical and mental fatigue in participants with Parkinson's, Huntington's, rheumatoid arthritis, systemic lupus erythematosus, primary Sjögren's syndrome and inflammatory bowel disease. Over 4 weeks, participants wore an IMU and reported fatigue levels four times daily. Using mixed-effects models, associations were identified between fatigue and specific kinematic features, such as 5th and 95th percentiles of sit-to-stand performance, suggesting that fatigue alters the control and effort of movement. These kinematic features show promise as indicators for fatigue in these patient populations.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.