Evidence map›Paper›PMID 39762420›Full record

Trial reportNature medicine2025

Ferric carboxymaltose for anemia in late pregnancy: a randomized controlled trial.

Sant-Rayn Pasricha, Ernest Moya, Ricardo Ataíde, Glory Mzembe, Rebecca Harding, Martin N Mwangi, Truwah Zinenani, Khic-Houy Prang, Justina Kaunda, Owen P L Mtambo and 11 more

Erratum issuedAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Sant-Rayn PasrichaWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia. pasricha.s@wehi.edu.au.ORCID 0000-0002-5502-0434
Ernest MoyaTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Ricardo AtaídeWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Glory MzembeTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Rebecca HardingWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID 0000-0003-4267-716X
Martin N MwangiTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.ORCID 0000-0002-8358-4448
Truwah ZinenaniTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Khic-Houy PrangCentre for Health Policy, Melbourne School of Population and Global Health, The University of Melbourne, Parkville, Victoria, Australia.
Justina KaundaTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Owen P L MtamboTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Maclean VokhiwaTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Gomezgani MhangoTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Elisabeth Mamani-MategulaTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Katherine FieldingWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Ayşe DemirDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.
Naomi Von DinklageWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Hans VerhoefDivision of Human Nutrition and Health, Wageningen University, Wageningen, The Netherlands.ORCID 0000-0002-9346-9689
Alistair Rd McLeanWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.
Lucinda Manda-TaylorTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi.
Sabine BraatWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.ORCID 0000-0003-1997-3999
Kamija S PhiriTraining and Research Unit of Excellence (TRUE), Blantyre, Malawi. kphiri@kuhes.ac.mw.ORCID 0000-0003-1753-2727

Funding

Department of Health | National Health and Medical Research Council (NHMRC) GNT2009047Gates Foundation INV-010612
6 · The paper itself

Abstract

Over 46% of African pregnant women are anemic. Oral iron is recommended but often suboptimal, particularly late in pregnancy. Intravenous ferric carboxymaltose (FCM) could treat anemia in women in the third trimester in sub-Saharan Africa. In an open-label, individually randomized trial in antenatal clinics in southern Malawi, we randomized 590 women at 27-35 weeks of gestation with capillary hemoglobin <10.0 g dl

Indexed as

AnemiaAnemia, Iron-DeficiencyFerric CompoundsMaltosePregnancy Complications, HematologicAdultBirth WeightFemaleHemoglobinsHumansInfant, NewbornMalawiPregnancyPregnancy Trimester, ThirdYoung Adultferric carboxymaltoseFerric CompoundsHemoglobinsMaltose

Identifiers

PMID39762420
PMCPMC11750709

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.