Evidence map›Paper›PMID 39762410›Full record

ArticleScientific reports2025

Association of Body Mass Index trajectory with thyroid nodules during young adulthood in China.

Hang Yan, Su Yan, Jingfeng Chen, Yang Yang, Suying Ding, Qian Qin

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hang YanHealth Management Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Su YanHealth Management Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Jingfeng ChenHealth Management Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yang YangHealth Management Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Suying DingHealth Management Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. fccdingsy@zzu.edu.cn.
Qian QinHealth Management Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. qinqianzzdx@126.com.

Funding

the Henan Province Medical Science and Technology Research Plan LHGJ20210354the Henan Province Medical Science and Technology Research Plan LHGJ20230317
6 · The paper itself

Abstract

This longitudinal study sought to identify distinct body mass index (BMI) trajectories and investigate the impact of these level-independent BMI trajectories on the prevalence of thyroid nodules (TN).This study encompassed a cohort of 1967 participants from a hospital in China. Utilizing latent class growth mixture modeling (LCGMM), four BMI trajectory groups were identified based on the BMI of individuals without TN from 2017 to 2019. The occurrence of TN in participants was monitored from 2020 to 2021. BMI trajectory classes and age were considered potential risk factors for TN development. After adjusting for covariates, the odds ratios (ORs) of model-estimated BMI levels were confirmed in the 27-50-year age group, ranging from 1.077 (1.000-1.158) to 1.189 (1.072-1.319). Significant associations between model-estimated BMI slope and TN were observed in the 21-47-year-old age group, with ORs varying between 1.270 (1.014, 1.591) and 2.490 (1.004, 6.174). The level-independent BMI trajectories throughout life significantly influenced the risk of TN prevalence. Moreover, controlling BMI growth rate in early adulthood (27-47 years old) emerged as a critical age window for reducing TN prevalence, underscoring its importance in TN prevention strategies.

Indexed as

Body Mass IndexThyroid NoduleAdultChinaFemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalenceRisk FactorsYoung AdultBody mass index slopeBody mass index trajectoryCohort studyLatent class growth mixture modelingThyroid nodule

Identifiers

PMID39762410
PMCPMC11704289

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.