Evidence map›Paper›PMID 39762362›Full record

ArticleScientific reports2025

Determination of antibacterial and antioxidant potential of organic crude extracts from Malus domestica, Cinnamomum verum and Trachyspermum ammi.

Asma Irshad, Rabbia Jawad, Qudsia Mushtaq, Alexis Spalletta, Patrick Martin, Uzair Ishtiaq

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Potential ofFood science & nutrition · 2026
    Article
  2. Article
  3. Review
  4. From Plant to Skin: ExploringAntioxidants (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Synergistic effects ofFrontiers in antibiotics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Asma IrshadSchool of Biochemistry and Biotechnology, University of the Punjab, Lahore, Pakistan.
Rabbia JawadSchool of Biological Sciences, University of the Punjab, Lahore, Pakistan.
Qudsia MushtaqMicrobial Biotechnology Laboratory, Institute of zoology, University of the Punjab, Lahore, Pakistan.
Alexis SpallettaUnité Transformations & Agroressources, ULR7519, Univ. Artois - Unilasalle, Béthune, F-62408, France.
Patrick MartinUnité Transformations & Agroressources, ULR7519, Univ. Artois - Unilasalle, Béthune, F-62408, France. Patrick.martin@univ-artois.fr.
Uzair IshtiaqDepartment of Research and Development, Paktex Industries, 2.5 KM Tatlay Road, Kamoke, Gujranwala, 52470, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants are the rich source of biologically active compounds which can be obliging against various pathogenic microorganisms and cancerous diseases. The current study evaluated the antibacterial potential of aqueous, methanol, ethanol, and acetone extracts of Malus domestica (apple), Cinnamomum verum (cinnamon) and Trachyspermum ammi (ajwain) via agar well diffusion methods and minimum inhibitory concentration (MIC) in (mm) against Staphylococcus aureus (ATCC 25923) and Salmonella typhi (ATCC 19430). The antioxidant properties including total phenolic content (TPC), total flavonoid content (TFC), DPPH and reducing power was determined by UV/VIS spectrophotometery and all the results interpreted through one way ANOVA (STATISTICA). In the results, methanolic and acetonic extracts of C. verum has shown maximum zone of inhibition (22.3 ± 0.58 mm) against S. aureus while for C. verum and T. ammi, ethanolic extracts has expressed the maximum zone of inhibition (22.3 ± 0.58 mm) against S. typhi and for M. domestica the methanolic extracts has exhibited highest zone of inhibition (18 ± 0.56 mm) among all other extracts of M. domestica. The MIC values were comparable with antimicrobial activity. Among the antioxidant activity analysis, the highest level of TPC has observed in aqueous extract of M. domestica 72.15 ± 1.80 mg GAE/g, while highest TFC was observed in methanolic extracts of M. domestica 15.62 ± 0.25 µg CE/g. The DPPH assay showed maximum percentage inhibition 123% in the methanolic extract of M. domestica, while highest reducing potential 13.42 ± 1.15 nm was observed in aqueous extract of C. verum. This study has compared three potential medicinal plants with biological active and eco-friendly components which play crucial role in therapeutics.

Indexed as

Anti-Bacterial AgentsAntioxidantsCinnamomum zeylanicumMalusMicrobial Sensitivity TestsPlant ExtractsStaphylococcus aureusFlavonoidsPhenolsSalmonella typhiAnti-Bacterial AgentsAntioxidantsFlavonoidsPhenolsPlant ExtractsAntimicrobialAntioxidantPlant extracts

Identifiers

PMID39762362
PMCPMC11704246

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.