Exploration of an adaptive proton therapy strategy using CBCT with the concept of digital twins.
Chih-Wei Chang, Zhen Tian, Richard L J Qiu, H Scott Mcginnis, Duncan Bohannon, Pretesh Patel, Yinan Wang, David S Yu, Sagar A Patel, Jun Zhou and 1 more
Article in Physics in medicine and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Chih-Wei ChangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.ORCID 0000-0002-3818-4381
Zhen TianDepartment of Radiation and Cellular Oncology, University of Chicago, Chicago, IL 60637, United States of America.
Richard L J QiuDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.ORCID 0000-0002-7877-1900
H Scott McginnisDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.
Duncan BohannonDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.
Pretesh PatelDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.
Yinan WangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.
David S YuDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.
Sagar A PatelDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.
Jun ZhouDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.ORCID 0000-0002-6078-9424
Xiaofeng YangDepartment of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA 30308, United States of America.ORCID 0000-0001-9023-5855
Funding
Translational and Clinical Trial Correlates CoreU54CA274513 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI Timothy An-thy Chan, David Sung-wen Yu · 2022 to 2026
$9.3M
Real-time Volumetric Imaging for Motion Management and Dose Delivery VerificationR01CA272991 · NCI · EMORY UNIVERSITY · PI Zhen Tian, Xiaofeng Yang · 2023 to 2026
$2.3M
Multiparametric MRI-guided Prostate HDR Brachytherapy with Focal Tumor BoostR01CA215718 · NCI · EMORY UNIVERSITY · PI YANG, XIAOFENG · 2018 to 2022
$1.8M
Artificial Intelligence Driven Automatic Treatment Planning of Stereotactic Radiosurgery for the Management of Multiple Brain MetastasesR37CA272755 · NCI · UNIVERSITY OF CHICAGO · PI Zhen Tian · 2022 to 2026
$1.8M
Intelligent and Personalized Online Adaptive Proton TherapyR01DE033512 · NIDCR · UNIVERSITY OF CHICAGO · PI Zhen Tian, Xiaofeng Yang · 2024 to 2026
$1.8M
Artificial Intelligence Driven Platform for PET/MR ImagingR56EB033332 · NIBIB · EMORY UNIVERSITY · PI MAO, HUI, YANG, XIAOFENG · 2022 to 2022
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Exploration of an adaptive proton therapy strategy using CBCT with the concept of digital twins. · full record | OpenQuestion