Evidence map›Paper›PMID 39761597›Full record

ArticleAmerican journal of respiratory cell and molecular biology2025

Hyaluronan Directs Alveolar Type II Cell Response to Acute Ozone Exposure in Mice.

Aaron Vose, Anastasiya Birukova, Michaela Albright, Adam Schlobohm, Stavros Garantziotis, Purushothama Rao Tata, Christina Barkauskas, Robert Tighe

Abstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Saving the lung from ozone pollutant: a new role of hyaluronan in alveolar regeneration.American journal of respiratory cell and molecular biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aaron VoseDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0003-2745-7070
Anastasiya BirukovaDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Michaela AlbrightDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Adam SchlobohmBiogen, Research Triangle Park, North Carolina.
Stavros GarantziotisNational Institute of Environmental Health Sciences, Durham, North Carolina; and.ORCID 0000-0003-4007-375X
Purushothama Rao TataDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0003-4837-0337
Christina BarkauskasDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.
Robert TigheDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Duke University, Durham, North Carolina.ORCID 0000-0002-3465-9861

Funding

INTERDISCIPLINARY TRAINING PROGRAM IN LUNG DISEASET32HL007538 · NHLBI · DUKE UNIVERSITY · PI LEE, PATTY J, PALMER, SCOTT M · 1985 to 2019
$7.2M
CXCL10/CXCR3 regulation of ozone-induced epithelial permeabilityR01ES027574 · NIEHS · DUKE UNIVERSITY · PI TIGHE, ROBERT MATTHEW · 2018 to 2022
$3.1M
Monocyte-derived alveolar macrophage drives inflammatory response to lung ozone exposureR01ES034350 · NIEHS · DUKE UNIVERSITY · PI Alexander Misharin, Robert Matthew Tighe · 2022 to 2026
$3.0M
NHLBI NIH HHS T32 HL007538NHLBI NIH HHS T32HL007538NIEHS NIH HHS R01 ES027574NIEHS NIH HHS R01 ES034350School of Medicine, Duke University
6 · The paper itself

Abstract

Becoming more frequent because of climate change, ozone (O

Indexed as

Alveolar Epithelial CellsHyaluronic AcidOzoneAcute Lung InjuryAnimalsBronchoalveolar Lavage FluidCell DifferentiationCell ProliferationHyaluronan SynthasesHyaluronoglucosaminidaseMaleMiceMice, Inbred C57BLHas2 protein, mouseHyaluronan SynthasesHyaluronic AcidHyaluronoglucosaminidaseOzonecell–matrix interactionclimate changelung injury

Identifiers

PMID39761597
PMCPMC12254692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.