Evidence map›Paper›PMID 39761387›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Pan-European atmospheric lead pollution, enhanced blood lead levels, and cognitive decline from Roman-era mining and smelting.

Joseph R McConnell, Nathan J Chellman, Andreas Plach, Sophia M Wensman, Gill Plunkett, Andreas Stohl, Nicole-Kristine Smith, Bo Møllesøe Vinther, Dorthe Dahl-Jensen, Jørgen Peder Steffensen and 4 more

Abstract readHistorical Article
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Environmental lead risk in the 21st century.Communications earth & environment · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Joseph R McConnellDivision of Hydrologic Sciences, Desert Research Institute, Reno, NV 89512.ORCID 0000-0001-9051-5240
Nathan J ChellmanDivision of Hydrologic Sciences, Desert Research Institute, Reno, NV 89512.ORCID 0000-0002-1117-1046
Andreas PlachDepartment of Meteorology and Geophysics, University of Vienna, Vienna 1090, Austria.ORCID 0000-0003-4899-5871
Sophia M WensmanDivision of Hydrologic Sciences, Desert Research Institute, Reno, NV 89512.
Gill PlunkettSchool of Natural and Built Environment, Queen's University Belfast, Belfast BT7 1NN, United Kingdom.ORCID 0000-0003-1014-3454
Andreas StohlDepartment of Meteorology and Geophysics, University of Vienna, Vienna 1090, Austria.ORCID 0000-0002-2524-5755
Nicole-Kristine SmithDivision of Hydrologic Sciences, Desert Research Institute, Reno, NV 89512.ORCID 0009-0003-4266-2774
Bo Møllesøe VintherPhysics of Ice, Climate and Earth, Niels Bohr Institute, University of Copenhagen, Copenhagen DK 2200, Denmark.
Dorthe Dahl-JensenPhysics of Ice, Climate and Earth, Niels Bohr Institute, University of Copenhagen, Copenhagen DK 2200, Denmark.ORCID 0000-0002-1474-1948
Jørgen Peder SteffensenPhysics of Ice, Climate and Earth, Niels Bohr Institute, University of Copenhagen, Copenhagen DK 2200, Denmark.ORCID 0000-0002-5516-1093
Diedrich FritzschePolar Terrestrial Environmental Systems, Alfred-Wegener-Institut Helmholtz-Zentrum für Polar-und Meeresforschung, Potsdam 14473, Germany.
Sandra O Camara-BruggerDepartment of Environmental Sciences, University of Basel, Basel 4056, Switzerland.ORCID 0000-0003-4188-2276
Brandon T McDonaldDivision of Hydrologic Sciences, Desert Research Institute, Reno, NV 89512.
Andrew I WilsonInstitute of Archaeology, University of Oxford, Oxford OX1 4PG, United Kingdom.ORCID 0000-0001-5237-2234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ancient texts and archaeological evidence indicate substantial lead exposure during antiquity that potentially impacted human health. Although lead exposure routes were many and included the use of glazed tablewares, paints, cosmetics, and even intentional ingestion, the most significant for the nonelite, rural majority of the population may have been through background air pollution from mining and smelting of silver and lead ores that underpinned the Roman economy. Here, we determined potential health effects of this air pollution using Arctic ice core measurements of Roman-era lead pollution, atmospheric modeling, and modern epidemiology-based relationships between air concentrations, blood lead levels (BLLs), and cognitive decline. Findings suggest air lead concentrations exceeded 150 ng/m

Indexed as

LeadMiningAir PollutantsAir PollutionChildCognitive DysfunctionEnvironmental ExposureEuropeFemaleHistory, AncientHumansMaleMetallurgyRoman WorldAir PollutantsLeadhuman healthintelligence quotientlead poisoninglead pollutionroman antiquity

Identifiers

PMID39761387
PMCPMC11760502

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.