ArticleeLife2025
Aminoglycoside tolerance in
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Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026Review
- Pyridoxal-phosphate-dependent biosynthesis of aminovaleramide by AvaS in tRNA.Nature chemical biology · 2026Article
- Anticodon nucleotide modifications affect translational tuning by the ribosomal CAR surface.bioRxiv : the preprint server for biology · 2026Article
- Defective queuosine and i6A/ms2i6A modification of tRNATyr cause frameshifting and protein aggregation.Nucleic acids research · 2026Article
- EnterohemorrhagicmSystems · 2026Article
- Growth-dependent tRNA Reprogramming and Codon Bias Link Translation to Metabolic State inbioRxiv : the preprint server for biology · 2026Article
- Remodeling of tRNA modification in Trypanosoma cruzi life forms.PLoS pathogens · 2026Article
- Unraveling the Prevalence and Multifaceted Roles of Accessory Peptide Deformylases in Bacterial Adaptation and Resistance.Molecular biology and evolution · 2025Article
- Beyond RNA modification: a novel role for tRNA modifying enzyme in oxidative stress response and metabolism.Nucleic acids research · 2025Article
- tRNA Modification Landscapes in Streptococci: Shared Losses and Clade-Specific Adaptations.bioRxiv : the preprint server for biology · 2025Article
- The tRNA epitranscriptomic landscape and RNA modification enzymes in Vibrio cholerae.PLoS genetics · 2025Article
- tRNA modifications as regulators of bacterial virulence and stress responses.PLoS pathogens · 2025Review
- tRNA-modifying enzymes in bacterial stress adaptation.Open biology · 2025Review
- Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters.Science advances · 2025Article
- Are Bacterial Processes Dependent on Global Ribosome Pausing Affected by tRNA Modification Defects?Journal of molecular biology · 2025Review
- Aminoglycoside tolerance ineLife · 2025Article
- Environmental Control of Queuosine Levels in Streptococcus mutans tRNAs.Molecular microbiology · 2025Article
- Queuosine salvage inMicrobiology (Reading, England) · 2024Article
- Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages.Microbiology and molecular biology reviews : MMBR · 2024Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors.
Louna Fruchard *Institut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.
Anamaria Babosan *Institut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.ORCID https://orcid.org/0000-0003-3464-5491
Andre CarvalhoInstitut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.
Manon LangInstitut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.
Blaise LiInstitut Pasteur, Université Paris Cité, Bioinformatics and Biostatistics Hub, Paris, France.ORCID https://orcid.org/0000-0003-3080-1899
Magalie DuchateauInstitut Pasteur, Université Paris Cité, Proteomics Platform, Mass Spectrometry for Biology Unit, Paris, France.ORCID https://orcid.org/0000-0001-5475-3065
Quentin Giai GianettoInstitut Pasteur, Université Paris Cité, Proteomics Platform, Mass Spectrometry for Biology Unit, Paris, France.
Mariette MatondoInstitut Pasteur, Université Paris Cité, Proteomics Platform, Mass Spectrometry for Biology Unit, Paris, France.ORCID https://orcid.org/0000-0003-3958-7710
Frederic BonhommeInstitut Pasteur, Université Paris cité, Epigenetic Chemical Biology Unit, Paris, France.
Isabelle HatinUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France.
Hugo ArbesUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France.
Céline FabretUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France.
Enora CorlerUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France.
Guillaume SanchezUniversité de Lorraine, CNRS, Inserm, UAR2008/US40 IBSLor, Epitranscriptomics and RNA Sequencing Core Facility and UMR7365 IMoPA, Nancy, France.
Virginie MarchandUniversité de Lorraine, CNRS, Inserm, UAR2008/US40 IBSLor, Epitranscriptomics and RNA Sequencing Core Facility and UMR7365 IMoPA, Nancy, France.ORCID https://orcid.org/0000-0002-8537-1139
Yuri MotorinUniversité de Lorraine, CNRS, Inserm, UAR2008/US40 IBSLor, Epitranscriptomics and RNA Sequencing Core Facility and UMR7365 IMoPA, Nancy, France.
Olivier NamyUniversité Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif sur Yvette, France.ORCID https://orcid.org/0000-0002-1143-5961
Valérie de Crécy-LagardDepartment of Microbiology and Cell Science, University of Florida, Gainesville, United States.ORCID https://orcid.org/0000-0002-9955-3785
Didier MazelInstitut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.ORCID https://orcid.org/0000-0001-6482-6002
Zeynep BaharogluInstitut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.ORCID https://orcid.org/0000-0003-3477-2685
Funding
Synthesis and function of Queuosine in BacteriaR01GM070641 · NIGMS · UNIVERSITY OF FLORIDA · PI DE CRECY-LAGARD, VALERIE A · 2006 to 2023
$5.3MLinking gene and function through comparative genomic and experimental approachesR35GM156215 · NIGMS · UNIVERSITY OF FLORIDA · PI Valerie A de Crecy-Lagard · 2025 to 2026
$1.3MAgence Nationale de la Recherche ANR-10-LABX-62-IBEIDAgence Nationale de la Recherche ANR-21-CE35-0012Agence Nationale de la Recherche ANR-24-CE12-7224-01Centre National de la Recherche Scientifique UMR3525Fondation pour la Recherche Médicale 202103012569Institut Pasteur Institut Pasteur Roux-Cantarini fellowshipInstitut Pasteur PTR 245-19NIGMS NIH HHS GM70641NIGMS NIH HHS R01 GM070641NIGMS NIH HHS R35 GM156215
Abstract
Tgt is the enzyme modifying the guanine (G) in tRNAs with GUN anticodon to queuosine (Q).
Indexed as
AminoglycosidesAnti-Bacterial AgentsProtein BiosynthesisRNA, TransferVibrio choleraeBacterial ProteinsGene Expression Regulation, BacterialAminoglycosidesAnti-Bacterial AgentsBacterial ProteinsRNA, Transferantibiotic stressepitranscriptomegeneticsgenomicsinfectious diseasemicrobiologypost-transcriptional regulationqueuosinetRNA modificationVibrio cholerae
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.