Evidence map›Paper›PMID 39760908›Full record

SynthesisIrish journal of medical science2025

Ultrasound-guided vs. laparoscopic-guided transversus abdominis plane block for postoperative pain following laparoscopic cholecystectomy: a systematic review and meta-analysis.

Abdullah Yousef Aldalati, Ayham Mohammad Hussein, Dang Nguyen, Cameron John Sabet, Bara M Hammadeh, Wesam I Abo-Elenien, Zaid Kamal, Ramez M Odat

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Irish journal of medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdullah Yousef AldalatiFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan. dalatia29@gmail.com.
Ayham Mohammad HusseinFaculty of Medicine, Al-Balqa' Applied University, Salt, Jordan.
Dang NguyenMassachusetts General Hospital, Corrigan Minehan Heart Center, Harvard Medical School, Boston, MA, USA.
Cameron John SabetGeorgetown University Medical Center, Washington, DC, USA.
Bara M HammadehFaculty of Medicine, Al-Balqa' Applied University, Salt, Jordan.
Wesam I Abo-ElenienClinical Department, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Zaid KamalDepartment of General Surgery, AdventHealth Medical Group, Tampa, FL, USA.
Ramez M OdatFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostoperative pain following laparoscopic cholecystectomy (LC) is a major concern. The transversus abdominis plane block (TAPB) is one of the anesthetic techniques that has been developed to address this issue. The TAPB can be delivered by the guidance of either ultrasound (UTAPB) or laparoscopic (LTAPB). Our aim is to compare the efficacy of these guidance methods in reducing postoperative pain after LC.

methodsA systematic search was performed in PubMed, Scopus, Cochrane, and Web of Science databases from inception to June 2024 for randomized studies comparing the delivery of TAPB under ultrasound and laparoscopic guidance. Data analysis was conducted using Review Manager V5.4.

resultsFive randomized studies were included in our study. UTAPB was significantly more effective in reducing postoperative pain after 6 h compared to LTAPB (MD =  - 0.38, 95% CI, - 0.67 to 0.09, p = 0.01). However, UTAPB was insignificantly more effective than LTAPB in reducing postoperative pain after 12 h (MD =  - 0.14, 95% CI, - 0.44 to 0.17, p = 0.39), 24 h (MD =  - 0.09, 95% CI, - 0.41 to 0.23, p = 0.60), and 48 h (MD =  - 0.12, 95% CI, - 0.44 to 0.19, p = 0.44). UTAPB insignificantly resulted in decreased opioid consumption (SMD: - 0.09; 95% CI: - 0.42, 0.25; p = 0.62) and less postoperative nausea and vomiting (OR = 0.73, 95% CI, 0.21 to 2.51, p = 0.62) in comparison with LTAPB.

conclusionUltrasound guidance of TAPB offers superior pain relief in the setting of LC, especially in the early postoperative period. Further trials are needed to prove and support the results.

Indexed as

Cholecystectomy, LaparoscopicLaparoscopyNerve BlockPostoperative PainUltrasonography, InterventionalAbdominal MusclesHumansRandomized Controlled Trials as TopicAbdominal muscles blockLaparoscopic cholecystectomyLocal anestheticsMeta-analysis

Identifiers

PMID39760908

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.