ArticleThe Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology2025
Impact of leadless pacemaker implantation site on cardiac synchronization and tricuspid regurgitation.
Article in The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Association Between Septal Implantation Level and Pacing Threshold Stability in Leadless Pacemaker Implantation.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundTo investigate the optimization of leadless pacemaker placement and to assess its impact on heart synchronization and tricuspid regurgitation.
resultsA clinical trial was conducted involving 53 patients who underwent leadless pacemaker implantation at the Second Affiliated Hospital of Zhejiang University School of Medicine and Hangzhou First People's Hospital between March 2022 and February 2023. Implantation site localization was determined using the 18-segment method under RAO 30° imaging. Intraoperative and 1-month post-operative echocardiography was performed to assess cardiac electromechanical synchronization and tricuspid regurgitation; parameters of interest included interventricular mechanical delay (IVMD), pre-ejection period of the aorta (L-PEI), and septal-to-posterior wall motion delay (SPWMD). Pacing thresholds, sensing, and impedance exhibited no significant differences between the 8/9 zone and other sites (P > 0.05). In contrast, the 8/9 zone group manifested a significant reduction in L-PEI (128.24 ± 12.27 vs. 146.50 ± 18.17 ms, P < 0.001), IVMD (17.92 ± 8.47 vs. 28.56 ± 15.16 ms, P < 0.001), and SPWMD (72.84 ± 19.57 vs. 156.56 ± 81.54 ms, P < 0.001), compared to the non-8/9 group. Post-pacing QRS duration showed no significant difference between the two groups (139.21 ± 11.36 vs. 143.83 ± 16.35 ms P = 0.310). Notably, for patients with atrial fibrillation, the 8/9 zone placement significantly reduced tricuspid regurgitation. During the 1-month follow-up, neither group reported major complications such as bleeding, cardiac tamponade, pacemaker detachment, or malignant arrhythmias.
conclusionImplantation of the leadless pacemaker in the right ventricular 8/9 zone provides superior electromechanical synchronization compared to other sites.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.