Evidence map›Paper›PMID 39760418›Full record

ArticleNeurourology and urodynamics2025

Sleep-Related Breathing Disorders and Lower Urinary Tract Dysfunction in Children and Adolescents: A Scoping Review.

Maayke van Galen, Bibi Huskens, Benodet Tak, Alexander von Gontard, Robert Didden

Abstract readScoping Review
In one paragraph

Article in Neurourology and urodynamics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maayke van GalenBehavioral Science Institute, Radboud University, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0002-2437-3819
Bibi HuskensBehavioral Science Institute, Radboud University, Nijmegen, The Netherlands.
Benodet TakSeysCentra, Malden, The Netherlands.
Alexander von GontardParent-Child and Adolescent Department, Hochgebirgsklinik Davos, Davos, Switzerland.ORCID http://orcid.org/0000-0002-3579-6200
Robert DiddenBehavioral Science Institute, Radboud University, Nijmegen, The Netherlands.ORCID http://orcid.org/0000-0001-5009-4269

Funding

This study was funded by SeysCentra.
6 · The paper itself

Abstract

aimsSleep disordered breathing (SDB), lower urinary tract dysfunction (LUTD), and enuresis (NE) are common in children and adolescents and have serious consequences, especially on social and emotional development. Even though much is known about the association between SDB and NE among adults, the number of articles in children and adolescents is limited. Therefore, the aim of the present scoping review was to map out the current knowledge about SDB and LUTD in children and adolescents.

methodsFour electronic databases (i.e., Embase, PsychInfo, Pubmed, Web of Science) were searched in accordance with the Johanna Briggs Institute (JBI) manual for Evidence Synthesis

resultsThe search resulted in the inclusion of 17 articles related to SDB and LUTD in children and adolescents. Even though all included articles found a clear association between SDB and NE in children, very limited information was found on SDB and other LUTS and/or how the association impacts children and adolescents with developmental delays (DD's). In addition, limited and/or conflicting results were found related to SDB, NE and other variables (e.g., family history of NE, obstructive sleep apnea (OSA) severity, gender, preoperative ADH/BNP levels, obesity and ADHD). An adenotonsillectomy (T&A) had a significant beneficial therapeutic effect on NE in children and adolescents with SDB.

conclusionsThis scoping review found a clear association between SDB/OSA and NE, as the arousability and urine production at night are impacted. T&A could be considered as a treatment option for children and adolescents who do not respond to standard NE treatment. However, more research is needed to determine mechanisms involved in responders and non-responders and to examine the possible association between SDB in children and adolescents with other LUTS and/or developmental delays. The need for a multidisciplinary approach and future research is highlighted to provide children and adolescents with comorbid disorders adequate care based on the understanding of underlying conditions and mechanisms involved.

Indexed as

EnuresisLower Urinary Tract SymptomsSleep Apnea SyndromesAdolescentChildChild, PreschoolFemaleHumansMaleadolescentschildrendevelopmental delays—scoping reviewenuresislower urinary tract dysfunction‐incontinenceobstructive sleep apneasleep‐related beathing disorders

Identifiers

PMID39760418
PMCPMC11788972

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.