Rectal Gas-Induced Dose Changes in Carbon Ion Radiation Therapy for Prostate Cancer: An In Silico Study.

Miyu Ishizawa, Yuya Miyasaka, Hikaru Souda, Takashi Ono, Hongbo Chai, Hiraku Sato, Takeo Iwai

Abstract read

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Article in International journal of particle therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

Patients with a Short Distance Between the Prostate and the Rectum Are Appropriate Candidates for Hydrogel Spacer Placement to Prevent Short-Term Rectal Hemorrhage After External-Beam Radiotherapy for Prostate Cancer.Current oncology (Toronto, Ont.) · 2025
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5 · Who and what money

Authors and funding

7 authors.

Miyu IshizawaDepartment of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.

Yuya MiyasakaDepartment of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.

Hikaru SoudaDepartment of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.

Takashi OnoDepartment of Radiation Oncology, Yamagata University Faculty of Medicine, Yamagata, Japan.

Hongbo ChaiDepartment of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.

Hiraku SatoDepartment of Radiation Oncology, Yamagata University Faculty of Medicine, Yamagata, Japan.

Takeo IwaiDepartment of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study aims to determine dosimetric influence of rectal gas in carbon ion radiation therapy (CIRT) for prostate cancer and to establish a procedure for removal rectal gas in clinical scenarios. Materials and methods: We analyzed 18 prostate cancer cases with bulky rectal gas. The dose distribution was recalculated on computed tomography (CT) with bulky rectal gas (gasCT) after creating the initial plan on a CT without bulky rectal gas, and the doses were transformed using a displacement vector field. This created a dose distribution simulation irradiated with the residual rectal gas. Among 12 fractions (fx) for prostate cancer CIRT, different residual rectal gas fx were used to develop 12 dose distributions, each of which was compared with that in the initial plan. Clinical target volume (D Results: The dosimetric changes in the clinical target volume were not significantly different from that in the initial treatment plan for both D Conclusion: Rectal gas removal may not be necessary up to 4 fx. Moreover, indicators related to dose changes based on DRR images were highly correlated with dose changes, revealing the possibilities of estimating dose changes due to rectal gas from kV-x-ray images and using gas effect evaluation during CIRT irradiation.

Indexed as

Carbon ion radiation therapyDose evaluationProstate cancerRectal gasTreatment planning study

Identifiers

PMID39760119

DOI10.1016/j.ijpt.2024.100637

PMCPMC11697597

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