Evidence map›Paper›PMID 39760001›Full record

ArticleHemaSphere2025

High levels of global hydroxymethylation predict worse overall survival in MDS patients treated with azacitidine.

Francesca Tiso, Florentien E M In 't Hout, Ruth Knops, Leonie I Kroeze, Arno van Rooij, Arjan A van de Loosdrecht, Theresia M Westers, Saskia M C Langemeijer, Claude Preudhomme, Nicolas Duployez and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Francesca TisoDepartment of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.ORCID https://orcid.org/0000-0002-3311-9476
Florentien E M In 't HoutDepartment of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.
Ruth KnopsDepartment of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.
Leonie I KroezeDepartment of Pathology Radboud University Medical Center Nijmegen The Netherlands.
Arno van RooijDepartment of Laboratory Medicine, Laboratory for Genetic, Endocrine, and Metabolic Diseases Radboud University Medical Center Nijmegen The Netherlands.
Arjan A van de LoosdrechtDepartment of Hematology, Cancer Center Amsterdam, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Theresia M WestersDepartment of Hematology, Cancer Center Amsterdam, Amsterdam UMC Vrije Universiteit Amsterdam Amsterdam The Netherlands.
Saskia M C LangemeijerDepartment of Hematology Radboud University Medical Center Nijmegen The Netherlands.
Claude PreudhommeDepartment Hematology Lille University Hospital Lille and INSERM UMR-S 1277 Lille France.
Nicolas DuployezDepartment Hematology Lille University Hospital Lille and INSERM UMR-S 1277 Lille France.ORCID 0000-0002-3927-1022
Pierre FenauxDepartment Hematology Hôpital Saint Louis, Assistance publique hôpitaux de paris, and Université de Paris Cité Paris France.
Olivier KosmiderDivision INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France.
Didier BouscaryDivision INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France.
Aniek O de GraafDepartment of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.
Joost H A MartensDepartment of Molecular Biology Radboud University Nijmegen The Netherlands.
Bert A van der ReijdenDepartment of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.
Lionel AdèsDepartment Hematology Hôpital Saint Louis, Assistance publique hôpitaux de paris, and Université de Paris Cité Paris France.
Michaela FontenayDivision INSERM U1016, Assistance Publique-Hôpitaux de Paris, Cochin Hospital and Université Paris Cité, CNRS, INSERM Cochin Institute Paris France.ORCID 0000-0002-5492-6349
Joop H JansenDepartment of Laboratory Medicine, Laboratory of Hematology Radboud University Medical Center and Radboud Institute for Molecular Life Sciences Nijmegen The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39760001
PMCPMC11695669

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.