Evidence map›Paper›PMID 39759982›Full record

ArticleAnnals of gastroenterological surgery2025

Effect of obesity on postoperative complications in ulcerative colitis: A systematic review and meta-analysis.

L M Tóth, H Székely, A Rancz, Á Zolcsák, M D Sárközi, S Ábrahám, L Földvári-Nagy, B Erőss, P Hegyi, P Miheller

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Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

L M TóthCentre for Translational Medicine Semmelweis University Budapest Hungary.ORCID https://orcid.org/0009-0004-1190-4053
H SzékelyCentre for Translational Medicine Semmelweis University Budapest Hungary.
A RanczCentre for Translational Medicine Semmelweis University Budapest Hungary.
Á ZolcsákDepartment of Biophysics and Radiation Biology, Faculty of Medicine Semmelweis University Budapest Hungary.
M D SárköziGeneral Medicine, Faculty of Medicine Semmelweis University Budapest Hungary.
S ÁbrahámDepartment of Surgery, Faculty of Medicine University of Szeged Szeged Hungary.
L Földvári-NagyDepartment of Morphology and Physiology, Faculty of Health Sciences Semmelweis University Budapest Hungary.
B ErőssCentre for Translational Medicine Semmelweis University Budapest Hungary.
P HegyiCentre for Translational Medicine Semmelweis University Budapest Hungary.
P MihellerDepartment of Surgery, Transplantation and Gastroenterology Semmelweis University Budapest Hungary.ORCID https://orcid.org/0000-0002-7396-3145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prevalence of ulcerative colitis (UC) is around 200/100 000 people. Colectomy is required in 7.5%-40% of patients and 58.8%-94% of these operations are elective. Approximately one in two adults with UC are overweight or obese. Objective: Our aim was to compare postoperative complications between obese (defined by a body mass index (BMI) over 30 kg/m Methods: Our preregistered protocol can be found on PROSPERO (CRD42022377761). We conducted our search in three databases on the 26th of November 2022. PRISMA 2020 guideline and the Cochrane Handbook were applied. We used the GRADEpro program and the QUIPS tool. We applied a random-effects model to pool effect sizes. We included cohort and case-control studies investigating UC patients undergoing colectomy with IPAA and reported information on postoperative complications in obese and non-obese patients. We used mean difference (MD) for continuous variables and calculated odds ratio (OR) with a 95% confidence interval (CI) for dichotomous variables. Results: Of the 6870 hits of our systematic search, we included three retrospective cohort studies for analyses involving 4929 patients in our research. Neither the incidence of complications at 30 days after surgery [OR = 1.08; CI: 0.65-1.79] nor the incidence of septic complications [OR = 1.11; CI: 0.85-1.46] had any clinical relevance, except for the length of hospital stay [MD = 0.36; CI:0.04-0.69]. When we assessed the risk of bias, we found that most of the aspects examined had a moderate overall risk. Our results have very low certainty of evidence. Conclusions and Relevance: Our findings suggest that obesity defined as BMI over 30 kg/m

Indexed as

inflammatory bowel diseasenutritional statusprehabilitationproctocolectomysurgical site infection

Identifiers

PMID39759982
PMCPMC11693578

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.