ArticleCureus2024
Accidental Organophosphate Poisoning in a Patient Due to a Bed Bug Pesticide in the United Kingdom: A Case Report.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Organophosphate (OP) compounds, developed during World War II, are a group of chemicals used as pesticides, insecticides and herbicides. As irreversible inhibitors of the enzyme acetylcholinesterase (AChE), they reduce anti-cholinesterase activity and therefore increase acetylcholine (ACh) levels at the neuromuscular junction (NMJ). Diazinon, the OP leading to the patient's symptoms in this report, is an amber-brown liquid that was once the most widely used insecticide in the United States of America. The patient inhaled diazinon and experienced a mixture of muscarinic and nicotinic receptor symptoms ranging from acute cholinergic syndrome to mild delayed intermediate syndrome. The patient was intubated, managed in the intensive care unit (ICU) with level 3 care, and made a full recovery. The report focuses on evolving toxicology advice and the adjustment of muscle relaxant dosing for intubation.
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