Evidence map›Paper›PMID 39759704›Full record

ReviewCureus2024

Dr. George Papanicolaou: Inventor of the Pap Smear and Father of Modern Cytology.

Abigail Dugas, Nadiya A Persaud, Latha Ganti

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Abigail DugasResearch, Orlando College of Osteopathic Medicine, Winter Garden, USA.
Nadiya A PersaudResearch, Orlando College of Osteopathic Medicine, Winter Garden, USA.
Latha GantiResearch, Orlando College of Osteopathic Medicine, Winter Garden, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Pap smear is widely recognized in medicine as the single most successful contributor to cancer screening and preventative care. Women have Dr. George Papanicolaou (1870-1962) to thank for this groundbreaking contribution to their healthcare-a discovery that, fascinatingly, was made incidentally during his study of ovulation cycles in guinea pigs. He found that vaginal smears from his subjects with cervical cancer, or those who later developed the disease, yielded abnormal cells that were notably discernible under a microscope when compared to healthy cells. Dr. Papanicolaou, both a physician and scientist, was a devoted researcher who conducted revolutionary studies alongside his wife at Cornell University for nearly 50 years. This paper will highlight the course of Dr. Papanicolau's life, how he found himself searching for his niche in the world of medicine and then scientific research, leading to his incidental discovery of the efficacy of the Pap smear in cancer screening and preventative measures. Dr. Papanicolau's legacy lives on through the contributions he made to the intersection of women's health with cancer prevention, and his devotion to his research continues to serve the field of medicine, now 50 years after his death.

Indexed as

biographiescytologyhistorical vignettemedical innovationmedical storiespap test

Identifiers

PMID39759704
PMCPMC11698546

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.