Evidence map›Paper›PMID 39759688›Full record

ArticleCureus2024

Precocious Puberty as a Unique Presentation of Hepatoblastoma in a Pediatric Patient: A Case Report.

Rachel Siretskiy, Monique Motta, Gabriela Aitken, Chelsea Spector, Claudia Rojas, Jill Whitehouse

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rachel SiretskiySurgery, Florida International University, Herbert Wertheim College of Medicine, Miami, USA.
Monique MottaPediatrics, Joe DiMaggio Children's Hospital, Hollywood, USA.
Gabriela AitkenSurgery, Memorial Healthcare System, Miami, USA.
Chelsea SpectorSurgery, Memorial Healthcare System, Miami, USA.
Claudia RojasAnatomic and Clinical Pathology, Pediatric Pathology, Memorial Healthcare System, Hollywood, USA.
Jill WhitehousePediatric Surgery, Joe DiMaggio Children's Hospital, Hollywood, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatoblastoma is a rare pediatric cancer. Hepatoblastoma typically presents asymptomatically with an enlarging abdominal mass but can be associated with paraneoplastic secretion of beta-gonadotropin leading it to present like peripheral precocious puberty. This case highlights a rare initial presentation of hepatoblastoma as precocious puberty in a two-year-old patient who presented with persistent abdominal and genital pain. The patient was treated with right hepatic lobectomy and subsequently two cycles of cisplatin and was considered to be in remission without concern for recurrent disease. Considering that there have been more reports of this pathology in recent years, it is crucial to discuss the presentation, diagnosis, and treatment of this pathology. This case emphasizes the importance of maintaining hepatoblastoma as a differential diagnosis when evaluating precocious puberty and abdominal pain to avoid delays in diagnosis and treatment. This article also highlights our team's approach to the workup and treatment of this pathology, which can serve as a roadmap for other clinicians.

Indexed as

hepatoblastomaparaneoplasticpediatricprecocious pubertysurgery

Identifiers

PMID39759688
PMCPMC11698537

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.