Evidence map›Paper›PMID 39759361›Full record

ReviewHeliyon2024

Carbon dot-based fluorescent sensors for pharmaceutical detection: Current innovations, challenges, and future prospects.

Sandesh R Lodha, Jesika G Merchant, Arya J Pillai, Anil H Gore, Pravin O Patil, Sopan N Nangare, Gajanan G Kalyankar, Shailesh A Shah, Dinesh R Shah, Shashikant P Patole

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sandesh R LodhaMaliba Pharmacy College, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli, 394350, Gujarat, India.
Jesika G MerchantMaliba Pharmacy College, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli, 394350, Gujarat, India.
Arya J PillaiMaliba Pharmacy College, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli, 394350, Gujarat, India.
Anil H GoreTarsadia Institute of Chemical Science, Uka Tarsadia University, Bardoli, 394350, Gujarat, India.
Pravin O PatilH.R Patel Institute of Pharmaceutical Education and Research, Shirpur, 425405, Maharashtra, India.
Sopan N NangareH.R Patel Institute of Pharmaceutical Education and Research, Shirpur, 425405, Maharashtra, India.
Gajanan G KalyankarMaliba Pharmacy College, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli, 394350, Gujarat, India.
Shailesh A ShahMaliba Pharmacy College, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli, 394350, Gujarat, India.
Dinesh R ShahMaliba Pharmacy College, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli, 394350, Gujarat, India.
Shashikant P PatoleDepartment of Physics, Khalifa University of Science and Technology, Abu Dhabi, 127788, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental contamination by pharmaceuticals has become a matter of concern as they are released in sewage systems at trace levels, thus impacting biological systems. Increasing concerns about the low-level occurrence of pharmaceuticals in the environment demands sensitive and selective monitoring. Owing to their high sensitivity and specificity carbon dots (CDs) have emerged as suitable fluorescent sensors. This review discusses the current scenario of the status of pharmaceuticals in the environment, limitations associated with traditional techniques employed for their detection, and benefits offered by CDs like easy surface modification and tunable optical properties for sensing applications. Several representative means by which CDs interact with other molecules such as inner filter effect (IFE), dynamic quenching (DQ), static quenching (SQ), Förster resonance energy transfer (FRET), among others, are also discussed along with co-referencing fluorophores to design sensors. Based on developments described herein, CDs-based sensors can be expected to sense pharmaceuticals ranging from nanogram to picogram, target real-time industrial and spiked sample analysis, etc., which provides direction for future research.

Indexed as

Carbon dotsFluorescent probeForster resonance energy transfer mechanismPharmaceutical detectionQuenching

Identifiers

PMID39759361
PMCPMC11697698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.