Evidence map›Paper›PMID 39759267›Full record

ArticleJournal of orthopedics for physician assistants

Diagnosis and Management of Legg-Calvé-Perthes Disease in the Obese Pediatric Population.

Lauren Beckish, Madison Ging, Maria Mosman, Cody Kelley, Landree Wilkin, Olivia Wills, Madison Adams, Cassidy Pinion, Cheyenne Bilica, Alavia Anderson and 3 more

Abstract read
In one paragraph

Article in Journal of orthopedics for physician assistants. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Lauren BeckishDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Madison GingDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Maria MosmanDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Cody KelleyDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Landree WilkinDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Olivia WillsDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Madison AdamsDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Cassidy PinionDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Cheyenne BilicaDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Alavia AndersonDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Margaret SimsDepartment of Physician Assistant Studies, West Liberty University, West Liberty, WV, United States of America.
Michael BeckishDepartment of Orthopedics, Prisma Health - Upstate, Greenville, SC, United States of America.
Deanna M SchmittDepartment of Biomedical Sciences, West Liberty University, West Liberty, WV, United States of America.

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI GARY O RANKIN · 2012 to 2026
$61.1M
NIGMS NIH HHS P20 GM103434
6 · The paper itself

Abstract

Legg-Calvé-Perthes Disease (LCPD) is a condition marked by temporary blood flow disruption to the proximal femur, commonly afflicting children aged 15 and younger. The etiology of the disease is often idiopathic and involves the development of avascular necrosis of the femoral head, subsequently leading to bone weakening and deformity. Obesity exacerbates LCPD, correlating with delayed diagnosis, increased disease severity, and bilateral involvement. Leptin, growth hormone, and other inflammatory mediator alterations in obese individuals contribute to the pathogenesis. Treatment ranges from conservative measures to surgery, with particular challenges in obese patients. An improved understanding of the impact of obesity on LCPD progression is crucial for tailored management and optimal outcomes.

Indexed as

Avascular NecrosisLegg-Calvé-Perthes DiseaseLegg-Calvé-Perthes disease progressionObesityOrthopedicsPediatrics

Identifiers

PMID39759267
PMCPMC11698501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.