Evidence map›Paper›PMID 39759090›Full record

ArticleNPP - digital psychiatry and neuroscience2025

Impaired arbitration between reward-related decision-making strategies in Alcohol Users compared to Alcohol Non-Users: a computational modeling study.

Srinivasan A Ramakrishnan, Riaz B Shaik, Tamizharasan Kanagamani, Gopi Neppala, Jeffrey Chen, Vincenzo G Fiore, Christopher J Hammond, Shankar Srinivasan, Iliyan Ivanov, V Srinivasa Chakravarthy and 2 more

Abstract read
In one paragraph

Article in NPP - digital psychiatry and neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Srinivasan A Ramakrishnan *Department of Health Informatics, Rutgers - School of Health Professions, Piscataway, NJ USA.
Riaz B Shaik *Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY USA.
Tamizharasan KanagamaniDepartment of Biotechnology, Indian Institute of Technology, Madras, Chennai India.
Gopi NeppalaDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY USA.
Jeffrey ChenUniversity of Pittsburgh School of Medicine, Pittsburgh, PA USA.ORCID 0000-0002-2768-2174
Vincenzo G FioreDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY USA.
Christopher J HammondDepartment of Psychiatry & Behavioral Sciences, Division of Child & Adolescent Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD USA.
Shankar SrinivasanDepartment of Health Informatics, Rutgers - School of Health Professions, Piscataway, NJ USA.
Iliyan IvanovDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY USA.
V Srinivasa ChakravarthyDepartment of Biotechnology, Indian Institute of Technology, Madras, Chennai India.
Wouter KoolDepartment of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO USA.
Muhammad A ParvazDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY USA.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
The Youth Opioid Recovery Support (YORS) Intervention: An assertive community treatment model for improving medication adherence in young adults with opioid use disorderR33DA056230 · NIDA · MARYLAND TREATMENT CENTERS, INC. · PI FISHMAN, MARC, HAMMOND, CHRISTOPHER J. · 2021 to 2022
$3.0M
Impact of Recreational and Medical Marijuana legalization on cannabis use disorders, serious mental illness, and mortality outcomes among Medicaid enrolled youthR01DA058303 · NIDA · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Cynthia Ann Fontanella, Christopher J. Hammond · 2023 to 2026
$2.6M
Characterization of Reward Processing in Adolescent Marijuana UseK01DA043615 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PARVAZ, MUHAMMAD ADEEL · 2018 to 2022
$855k
Cue Reactivity Modulation in MSM with Methamphetamine Use DisorderR61DA056779 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PARVAZ, MUHAMMAD ADEEL · 2023 to 2024
$828k
Cognitive Reappraisal for Mitigating Incubation of Cocaine Cue-ReactivityR01DA058039 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI PARVAZ, MUHAMMAD ADEEL · 2023 to 2023
$816k
NCATS NIH HHS UL1 TR004419NIDA NIH HHS K01 DA043615NIDA NIH HHS R01 DA058039NIDA NIH HHS R01 DA058303NIDA NIH HHS R33 DA056230NIDA NIH HHS R61 DA056779
6 · The paper itself

Abstract

Reinforcement learning studies propose that decision-making is guided by a tradeoff between computationally cheaper model-free (habitual) control and costly model-based (goal-directed) control. Greater model-based control is typically used under highly rewarding conditions to minimize risk and maximize gain. Although prior studies have shown impairments in sensitivity to reward value in individuals with frequent alcohol use, it is unclear how these individuals arbitrate between model-free and model-based control based on the magnitude of reward incentives. In this study, 81 individuals (47 frequent Alcohol Users and 34 Alcohol Non-Users) performed a modified 2-step learning task where stakes were sometimes high, and other times they were low. Maximum

Indexed as

Cognitive neuroscienceHuman behaviour

Identifiers

PMID39759090
PMCPMC11698690

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.