Evidence map›Paper›PMID 39758983›Full record

ArticleiScience2024

Epidemiological insights into severe hepatitis in pediatric inpatients.

Fuping Guo, Xudong Ma, Qijun Shan, Yuelun Zhang, Sifa Gao, Jieqin Chen, Yujie Chen, Dawei Liu, Taisheng Li, Feng Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fuping GuoDepartment of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Xudong MaDepartment of Medical Administration, National Health Commission of the People's Republic of China, Beijing 100044, China.
Qijun ShanDepartment of Information Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Yuelun ZhangCentral Research Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Sifa GaoDepartment of Medical Administration, National Health Commission of the People's Republic of China, Beijing 100044, China.
Jieqin ChenDepartment of Information Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Yujie ChenDepartment of Information Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Dawei LiuDepartment of Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Taisheng LiDepartment of Infectious Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Feng ZhangDepartment of Information Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Xiang ZhouDepartment of Information Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
China Critical Care Clinical Trials Group (CCCCTG) and China National Critical Care Quality Control Center Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is limited statistical data on severe hepatitis among hospitalized children in China at a national level. This nationwide study analyzed data from 34,410 children hospitalized for severe hepatitis in mainland China from 2016 to 2022. The overall in-hospital mortality rate was 6.1%. Viral hepatitis accounted for 14.9% of cases, with hepatitis B being the most prevalent. Indeterminate etiology, present in 79.0% of cases, was an independent risk factor for mortality. Findings emphasize the need for enhanced diagnostic methods and targeted interventions for children with severe hepatitis of unknown cause and suggest focused hepatitis B monitoring in older children to improve outcomes. Establishing a dedicated surveillance system is crucial for improving the prognosis of children at high risk for in-hospital mortality due to severe hepatitis.

Indexed as

Health scienceshepatologymedicine

Identifiers

PMID39758983
PMCPMC11699462

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.