Evidence map›Paper›PMID 39758980›Full record

ArticleiScience2024

Zinc finger protein 593 promotes breast cancer development by ensuring DNA damage repair and cell-cycle progression.

Yingfan Zhang, Xiaowen Tang, Chenxin Wang, Mozhi Wang, Meng Li, Xiang Li, Litong Yao, Yingying Xu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingfan ZhangDepartment of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Xiaowen TangDepartment of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Chenxin WangDepartment of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Mozhi WangDepartment of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Meng LiGeneral Surgery Department, Dandong Central Hospital, China Medical University, Dandong, Liaoning, China.
Xiang LiDepartment of Ultrasound, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Litong YaoDepartment of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Yingying XuDepartment of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer, a common malignancy and top cause of female cancer deaths globally, urgently requires new biomarkers and insights into its progression and chemoresistance. In this study, we identify ZNF593, a member of the zinc finger protein family, as an understudied oncogene in breast cancer. ZNF593 is significantly upregulated in breast cancer tissues compared to adjacent normal tissues, which is linked to poor prognosis and advanced clinicopathological features.

Indexed as

BiochemistryBiological sciencesCancerProtein

Identifiers

PMID39758980
PMCPMC11699609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.