Evidence map›Paper›PMID 39758860›Full record

ArticleCureus2025

First Bite Syndrome: A Rare Post-Surgical Complication Following a Carotid Body Tumor Excision.

Noura M AlOtaibi, Ali N Alanzan, Abdulaziz K Aloshaywi, Naif H Alotaibi, Abdulkarim F Alanazi, Faris M Alrajhi, Jawza Meaadi

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Analysis of clinical characteristics of 12 cases of first bite syndrome].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noura M AlOtaibiOral and Maxillofacial Surgery, University of Glasgow, Glasgow, GBR.
Ali N AlanzanDentistry, King Saud University, Riyadh, SAU.
Abdulaziz K AloshaywiDentistry, King Saud University, Riyadh, SAU.
Naif H AlotaibiDentistry, King Saud University, Riyadh, SAU.
Abdulkarim F AlanaziDentistry, King Saud University, Riyadh, SAU.
Faris M AlrajhiDentistry, King Saud University, Riyadh, SAU.
Jawza MeaadiClinical Pharmacy and Neurology, King Saud Medical City, Riyadh, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

First bite syndrome (FBS) is characterized by intense pain in the parotid area that starts with the first bite of food spontaneously. FBS is an uncommonly observed surgical complication of head and neck surgery. A 36-year-old male patient reported extreme pain after surgical excision of a carotid body tumor (CBT) in the ipsilateral parotid gland region at the first bite of each food intake, which improves gradually with continued mastication. Several factors are believed to be responsible for this phenomenon, including injury or amputation of the cervical sympathetic trunk. Loss of sympathetic innervation makes the parotid gland hypersensitive to parasympathetic stimulation. The best treatment for FBS is not yet firmly established, even though symptoms tend to improve with time in some cases. We report this case of FBS after CBT excision to raise awareness among maxillofacial surgeons of this surgical complication.

Indexed as

first bitemaxillofacial tumor surgeryneck surgeryparotid painsevere pain

Identifiers

PMID39758860
PMCPMC11695805

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.