Evidence map›Paper›PMID 39758781›Full record

ArticleFrontiers in neurology2024

Dynamic fluctuations in brain iron content during migraine attacks: insights from relaxometry and diffusion tensor imaging.

Christoph Birkl, Vera Filippi, Ruth Steiger, Florian Frank, Stephanie Magnesius, Elke R Gizewski, Gregor Broessner

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christoph BirklDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Vera FilippiDepartment of Neurology, Headache Outpatient Clinic, Medical University of Innsbruck, Innsbruck, Austria.
Ruth SteigerDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Florian FrankDepartment of Neurology, Headache Outpatient Clinic, Medical University of Innsbruck, Innsbruck, Austria.
Stephanie MagnesiusDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Elke R GizewskiDepartment of Neuroradiology, Medical University of Innsbruck, Innsbruck, Austria.
Gregor BroessnerDepartment of Neurology, Headache Outpatient Clinic, Medical University of Innsbruck, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There is evidence that iron metabolism may play a role in the underlying pathophysiological mechanism of migraine. Studies using Purpose: To investigate whether there are short-term changes in Population: 26-year-old male patient diagnosed with episodic migraine with aura according to ICHD-3 criteria. Sequence: 3 T, 64-channel head coil, for quantification of Assessment: Quantitative MRI, including Statistical test: Statistical analysis was performed using R, the Shapiro-Wilk test, the Results: Significant difference in Data conclusion: Our study showed a decrease and increase in iron content during the migraine cycle. Furthermore, during a migraine attack, white matter iron content increased, accompanied by a decrease in anisotropic tissue components, suggesting additional changes in vascular components.

Indexed as

brain ironmigraine cyclepain processingquantitative MRIR2* relaxometry

Identifiers

PMID39758781
PMCPMC11697585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.