SynthesisFrontiers in neurology2024
Optimal proprioceptive training combined with rehabilitation regimen for lower limb dysfunction in stroke patients: a systematic review and network meta-analysis.
Synthesis in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Comparative effectiveness of neuromuscular electrical stimulation-based combination interventions for post-stroke lower limb rehabilitation: a systematic review and network meta-analysis.Journal of neuroengineering and rehabilitation · 2026Pooled it
- Network meta-analysis of different electrical stimulation therapies for lower limb functional rehabilitation in stroke patients.Frontiers in neurology · 2025Pooled it
- Comparison of the effects of transcranial direct current stimulation combined with different rehabilitation interventions on motor function in people suffering from stroke-related symptoms: a systematic review and network meta-analysis.Frontiers in neurology · 2025Pooled it
- Article
- Unveiling the Clinical Impact of Lower Limb Robotic Devices in Neurorehabilitation: An Umbrella Review.Annals of biomedical engineering · 2026Review
- Evaluating core stability training-based combination therapies for lower extremity dysfunction post-stroke: a systematic review and network meta-analysis.BMC sports science, medicine & rehabilitation · 2025Article
- Comparative Recovery After Acute Lower-Limb Wounds Treated with Negative-Pressure Wound Therapy and Three Gradations of Manual Rehabilitation.Healthcare (Basel, Switzerland) · 2025Article
- Acupuncture for Post-Stroke Lower Limb Dysfunction: Clinical Efficacy and Neurophysiological Mechanisms.Journal of multidisciplinary healthcare · 2025Review
- Capsular warning syndrome followed by right internal capsule infarction: A case report emphasising post-stroke rehabilitation.SAGE open medical case reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aims to evaluate the optimal rehabilitation regimen for lower limb dysfunction in stroke patients by analyzing the effects of proprioceptive training (PT) in combination with different rehabilitation interventions. Methods: Randomized controlled trials (RCTs) published up to April 23, 2024, were searched from PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, VIP, and SinoMed. The quality of the included studies was assessed using the Cochrane Risk of Bias tool (ROB 2.0). Network meta-analysis was performed via R studio and STATA 15.0. Results: A total of 64 RCTs involving 4,084 stroke patients with lower limb dysfunction were included. For balance ability in stroke patients, PT in combination with motor relearning programme (PT + MRP) demonstrated the optimal rehabilitation effect [surface under the cumulative ranking curve (SUCRA) 77.94%]. For lower limb motor function, PT in combination with closed kinematic chain exercises (PT + CKCE) was most effective (SUCRA 88.39%). For walking ability, PT in combination with visual feedback training (PT + VFT) was superior (SUCRA 96.61%). Cluster analysis indicated that PT + CKCE and PT + RT1 were the optimal rehabilitation regimens for lower limb dysfunction in stroke patients. Conclusion: PT+MRP was the optimal rehabilitation regimen for improving balance ability in stroke patients; PT+CKCE was the best for enhancing lower limb motor function; and PT+VFT was most effective for improving walking ability. Overall, PT+CKCE and PT+RT1 represented the optimal rehabilitation regimens for lower limb dysfunction in stroke patients, while PT+RT1 is most effective within 5 days of stroke onset. Systematic review registration: https://www.crd.york.ac.uk/PROSPERO/#recordDetailsCRD42024548889, PROSPERO CRD42024548889.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.