Protective effects of a novel FS-Collagen hydrolysates against UV- and d-galactose-induced skin aging.

Yihan Zhang, Guangye Huang, Zhen Zhang, Yongzhao Xu, Jiaoyan Ren, Wei Sun, Jianwen Chen, Ruikun He

Abstract read

In one paragraph

Article in Food science and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yihan Zhang *School of Biology and Biological Engineering, South China University of Technology, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, China.

Guangye Huang *School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, China.

Zhen ZhangBYHEALTH Institute of Nutrition & Health, Kexue Avenue Central, Huangpu District, Guangzhou, China.

Yongzhao XuSchool of Food Sciences and Engineering, South China University of Technology, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, China.

Jiaoyan RenSchool of Food Sciences and Engineering, South China University of Technology, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, China.

Wei SunSchool of Food Sciences and Engineering, South China University of Technology, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, China.

Jianwen ChenSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou Higher Education Mega Center, Panyu District, Guangzhou, China.

Ruikun HeBYHEALTH Institute of Nutrition & Health, Kexue Avenue Central, Huangpu District, Guangzhou, China.ORCID 0000-0002-2292-8884

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The oral consumption of collagen hydrolysates derived from various animal tissues has been demonstrated to have beneficial effects on skin health, particularly in combating the signs of aging. Here in this study, a novel animal-derived FS-Collagen hydrolysates were developed and its effects against skin aging was analyzed in a new mice skin aging model established through a combination of UV irradiation and d-galactose induction. 8 Weeks of oral FS-Collagen administration demonstrated significant protective effects against skin aging in mice, evidenced by the preservation of the skin's macroscopic appearance, the restoration of skin composition and structure, an enhancement in antioxidant capacity and the inhibition of inflammation. Additionally, FS-Collagen safeguards skin barrier integrity and cellular connections, particularly by maintaining the expression levels of Dsg1 and Jam-A. In summary, the FS-Collagen exhibits positive effects in countering skin aging and holds promise as an alternative functional nutrition supplement for anti-skin aging care. Supplementary Information: The online version contains supplementary material available at 10.1007/s10068-024-01660-7.

Indexed as

Cellular connectionsCollagen hydrolysatesCollagen IHyaluronic acidSkin aging

Identifiers

PMID39758722

DOI10.1007/s10068-024-01660-7

PMCPMC11695533

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.