Evidence map›Paper›PMID 39758616›Full record

ArticleACS omega2024

Molding Quality and Biological Evaluation of a Two-Stage Titanium Alloy Dental Implant Based on Combined 3D Printing and Subtracting Manufacturing.

Hongbo Wei, Shitou Huang, Yi Liu, Dehua Li

Abstract read
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongbo WeiState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.ORCID https://orcid.org/0000-0001-5167-031X
Shitou HuangState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.
Yi LiuState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.
Dehua LiState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration & National Clinical Research Center for Oral Diseases & Shaanxi Engineering Research Center for Dental Materials and Advanced Manufacture, Department of Oral Implants, School of Stomatology, The Fourth Military Medical University, Xi'an 710032, Shaanxi, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal 3D printing has been used in the manufacturing of dental implants. Its technical advantages include high material utilization and the capacity to form arbitrarily complex structures. However, 3D printing alone is insufficient for manufacturing two-stage titanium implants due to the limited precision in printing titanium alloy parts. In this study, 3D printing was employed to create the implant structure, subsequently complemented by mechanical processing to refine the implant abutment connection and neck. Additionally, the mechanical properties of 3D-printed titanium alloy implants were evaluated through tensile and dynamic fatigue testing. The MTT assay was employed to assess the cytotoxicity of 3D-printed titanium alloy dental implants. The impact of bone union and osteogenesis from 3D-printed titanium alloy dental implants was investigated through in vivo experimentation. The results demonstrated that combining 3D printing with subsequent machining constitutes a viable method for the manufacture of two-stage titanium dental implants. Test results for mechanical properties indicated that heat-treated 3D-printed titanium alloy dental implants possess significant tensile strength and fatigue resistance and are capable of withstanding the robust chewing forces in the oral cavity. In vitro findings revealed that sandblasted and acid-etched 3D-printed titanium alloy exhibited negligible cytotoxicity, with osteoblast differentiation of hMSCs being more pronounced compared with the control group. In vivo studies indicated that no significant differences were observed in bone volume fraction, bone-implant contact rate, and unscrewing torque between 3D-printed titanium alloy dental implants and commercial SLA surface implants at both 1 and 3 months postimplantation.

Identifiers

PMID39758616
PMCPMC11696423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.