Evidence map›Paper›PMID 39758557›Full record

ArticleJournal of mood and anxiety disorders2025

Structure-function coupling in network connectivity and associations with negative affectivity in a group of transdiagnostic adolescents.

Dana Kanel, Andre Zugman, Grace Stohr, Beck Scheinberg, Elise Cardinale, Anderson Winkler, Katharina Kircanski, Nathan A Fox, Melissa A Brotman, Julia O Linke and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of mood and anxiety disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dana KanelDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD.
Andre ZugmanEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Grace StohrEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Beck ScheinbergThe Pennsylvania State University Department of Psychology - Child Clinical Track.
Elise CardinaleEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Anderson WinklerEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Katharina KircanskiEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Nathan A FoxDepartment of Human Development and Quantitative Methodology, University of Maryland, College Park, MD.
Melissa A BrotmanEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
Julia O LinkeDepartment of Psychology, University of Freiburg, Freiburg, Germany.
Daniel S PineEmotion and Development Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.

Funding

Fmri Studies Of Risk For Mood And Anxiety Disorders In ChildrenZIAMH002782 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PINE, DANIEL · 2009 to 2025
$28.3M
Intramural NIH HHS ZIA MH002782
6 · The paper itself

Abstract

The study of brain connectivity, both functional and structural, can inform us on the development of psychopathology. The use of multimodal MRI methods allows us to study associations between structural and functional connectivity, and how this relates to psychopathology. This may be especially useful during childhood and adolescence, a period where most forms of psychopathology manifest for the first time. The current paper explores structure-function coupling, measured through diffusion and resting-state functional MRI, and quantified as the correlation between structural and functional connectivity matrices. We investigate associations between psychopathology and coupling in a transdiagnostic group of adolescents, including many treatment-seeking youth with relatively high levels of symptoms (

Indexed as

adolescenceanxietyconnectomescouplingdiffusion MRIfMRIirritability

Identifiers

PMID39758557
PMCPMC11694614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.