Evidence map›Paper›PMID 39758399›Full record

ArticleHeliyon2025

Age-related differences in eye blink-related neural activity and functional connectivity during driving.

Emad Alyan, Stefan Arnau, Stephan Getzmann, Julian Elias Reiser, Melanie Karthaus, Edmund Wascher

Abstract read
In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emad AlyanDepartment of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Stefan ArnauDepartment of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Stephan GetzmannDepartment of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Julian Elias ReiserDepartment of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Melanie KarthausDepartment of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.
Edmund WascherDepartment of Ergonomics, Leibniz Research Centre for Working Environment and Human Factors, 44139, Dortmund, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Driving is a complex task that requires effective neural processing and coordination, which degrade with aging. Previous studies suggest that age-related changes in cognitive and motor functions can influence driving performance. Herein, we investigated age-related differences and differences between reactive and proactive driving in blink behavior-related potentials, and source-level functional connectivity. Seventy-six subjects participated in two experiments with reactive (19 young, 28 older) and proactive (16 young, 13 older) driving scenarios, consisting of a lane-keeping task with either varying levels of crosswind or curve road, respectively. While blink rate analysis revealed no significant age or driving condition effects, blink duration was notably longer in younger participants. Also, significant age effects were observed in blink-related potentials, mainly in the frontal N2 and occipital P0 and P2 components, with higher amplitudes in younger participants, signifying more efficient neural processing. The parietal N2 component showed significant age and interaction effects, with older individuals showing higher amplitudes in reactive conditions, potentially due to increased cognitive effort and attentional demands. Furthermore, functional connectivity analysis revealed that aging most significantly affects the visual network in the beta band. More specifically, younger participants showed an increase in the clustering coefficient and degrees of the networks, reflecting more robust neural network integration. This pattern of higher connectivity measures in younger participants was also observed in the default mode, control, and limbic networks. Conversely, the dorsal attention network in the theta band showed an increased degree and clustering coefficient in older adults, which could indicate a compensatory mechanism for maintaining cognitive demands. This study highlights the impact of aging on neural activity and connectivity characteristics during driving and emphasizes the requirement of age-tailored interventions, aimed to improve driving safety.

Indexed as

AgingBlink-related EEGDrivingEye behaviorFunctional connectivity

Identifiers

PMID39758399
PMCPMC11699334

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.