ArticleJournal of advanced periodontology & implant dentistry2024
Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial.
Article in Journal of advanced periodontology & implant dentistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed.
- Trial
- Non-Surgical Cosmetic Treatment Modalities for Interdental Papilla Reconstruction "Black Triangles": An Evidence-Based Review.Journal of cosmetic dermatology · 2026Review
- Clinical effectiveness of albumin-enriched platelet-rich fibrin (Alb-PRF) in periodontal and peri-implant regenerative surgery: a systematic review.Odontology · 2026Review
- Effectiveness of hyaluronic acid vs. surgical and non-surgical methods for Papilla Reconstruction: a systematic review.Frontiers in dental medicine · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The interdental papilla plays a crucial role in the esthetic of the smile. Papilla reconstruction surgery is one of the most unpredictable periodontal procedures. This study compared the effect of the non-surgical application of a commercial hyaluronic acid (HA) gel with an autogenous gel named "albumin with platelet-rich fibrin" (Alb-PRF) on interdental papilla reconstruction. Methods: This trial was conducted on 46 incomplete interdental papillae with class I or II defects. The papillae were randomly divided into two experimental groups, and commercial HA or Alb-PRF (prepared from the patient's peripheral blood) was injected into the papillae twice at a 21-day interval. Three and six months after the intervention, photographs were taken from the black triangles and the black surfaces compared to each other. Patient satisfaction and dental plaque index were also evaluated at the end of the study. Results: The black triangles' surfaces significantly decreased over time in both experimental groups ( Conclusion: HA or Alb-PRF injection into the incomplete interdental papilla may restore the soft tissue to a great extent and lead to patient satisfaction by reducing the area of black triangles that threaten esthetics; however, more studies are needed.
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Registered trials
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