ArticleNational science review2025
DNA palette code for time-series archival data storage.
Article in National science review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- DNA-Based Boolean Logic Gates for Molecular Computation and Biosensing: A Critical Review.Molecular biotechnology · 2026Review
- Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning.Synthetic and systems biotechnology · 2026Article
- DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage.Nature communications · 2025Article
- DNA-CTMF: Reconstruct high quality image from lossy DNA storage via Pixel-Base codebook and median filter.Synthetic and systems biotechnology · 2025Article
- Directed assembly of single-stranded DNA fragments for data storage via protein-free catalytic splint ligation.Nucleic acids research · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The long-term preservation of large volumes of infrequently accessed cold data poses challenges to the storage community. Deoxyribonucleic acid (DNA) is considered a promising solution due to its inherent physical stability and significant storage density. The information density and decoding sequence coverage are two important metrics that influence the efficiency of DNA data storage. In this study, we propose a novel coding scheme called the DNA palette code, which is suitable for cold data, especially time-series archival datasets. These datasets are not frequently accessed, but require reliable long-term storage for retrospective research. The DNA palette code employs unordered combinations of index-free oligonucleotides to represent binary information. It can achieve high net information density encoding and lossless decoding with low sequencing coverage. When sequencing reads are corrupted, it can still effectively recover partial information, preventing the complete failure of file retrieval. The
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.