Evidence map›Paper›PMID 39757663›Full record

ArticleCurrent medical imaging2025

Intracranial Structural Malformations in Children in Tibet: CT and MRI Findings in a Single Tertiary Center.

Xuan Yin, Dawa Ciren, Ciren Guojie, Guofu Zhang, Jimei Wang, He Zhang

Abstract read
In one paragraph

Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xuan YinDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, P.R.China.
Dawa CirenDepartment of Radiology, Shigatse People's Hospital, Shigatse, Xianzang Autonomous Region, P.R.China.
Ciren GuojieDepartment of Radiology, Shigatse People's Hospital, Shigatse, Xianzang Autonomous Region, P.R.China.
Guofu ZhangDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, P.R.China.
Jimei WangDepartment of Neonatology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, P.R.China.
He ZhangDepartment of Radiology, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, P.R.China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to summarize the findings of children's intracranial congenital or developmental malformations found during imaging procedures in the Tibetan plateau.

methodsWe retrospectively reviewed the imaging data of the suspected patients who presented with the central nervous system (CNS) malformations and were enrolled either through the clinic or after ultrasound examinations between June 2019 and June 2023 in our institution. All imaging data were interpreted by two experienced radiologists through consensus reading.

resultsIn this study, we recruited 36 patients, including two neonates, 17 infants and 17 children. Seven cases underwent an MRI examination, while the others had a CT scan. Polygyria and pachygyria malformation were the most common type of congenital neurological malformations (7 cases, 31.8%), followed by cystic changes of the cerebral parenchyma (3 cases, 13.6%). Cerebral atrophy was the most common type of secondary CNS abnormality(8 cases, 57.1%), followed by communicative hydrocephalus (3 cases, 21.4%). Five patients in the congenital group and 4 patients in the secondary group had complex malformations. In the current study group, there were 8 deaths, 12 cases with neurological sequelae, 1 case with normal development, and 15 cases lost to follow-up. There were no significant differences between the primary and secondary CNS groups in terms of the outcome for both the infants and children groups.

conclusionsCNS malformations in the Tibetan Plateau are associated with high mortality and morbidity rates. Better utilization of imaging modalities could help design tailored treatments as early as possible.

Indexed as

BrainMagnetic Resonance ImagingNervous System MalformationsTomography, X-Ray ComputedAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleRetrospective StudiesTertiary Care CentersTibetAbnormalitiesCentral nervous systemComputed tomographyInfantMagnetic resonance imaging. ArticleNewborn

Identifiers

PMID39757663
PMCPMC12813543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.