Evidence map›Paper›PMID 39757633›Full record

ArticleCurrent neurovascular research2025

CT Perfusion Metrics as Indicators of Intracranial Atherosclerotic Stenosis in Acute Ischemic Stroke: A Clinical Analysis.

Yunpeng Liu, Jumei Huang, Jianwen Jia, Yingting Zuo, Yang Wang, He Liu

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Article in Current neurovascular research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Yunpeng LiuDepartment of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Jumei HuangDepartment of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Jianwen JiaDepartment of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Yingting ZuoDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yang WangDepartment of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
He LiuDepartment of Neurosurgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntracranial Atherosclerotic Stenosis (ICAS) is a prevalent etiology of acute ischemic stroke (AIS), leading to significant morbidity and mortality. The accurate diagnosis and treatment of ICAS-induced AIS are critical to improving outcomes. This study assesses the application of Computed Tomography Perfusion (CTP) in predicting ICAS in AIS patients and its potential impact on patient management.

methodsA retrospective analysis was conducted on 224 AIS patients who underwent endovascular therapy (EVT) at one single Chinese Stroke Center between April 2022 and December 2023. Clinical and radiological data were collected, including patients' demographics, CTP parameters, and 90-day modified Rankin Scale (mRS) scores. Logistic regression and receiver operating characteristic (ROC) curves evaluated the predictive power of CTP parameters for ICAS.

resultsCTP analysis revealed significant differences in perfusion parameters between ICASinduced AIS and other etiologies. ICAS patients had a smaller ischemic volume on admission and higher mismatch ratios [Time to Maximum, T

conclusionCTP is a valuable diagnostic tool for ICAS-induced AIS, offering the potential for early identification and informing the decision for endovascular treatment. The positive correlation between CTP findings and patient outcomes supports its utility in clinical practice.

Indexed as

Cerebrovascular CirculationIntracranial ArteriosclerosisIschemic StrokeTomography, X-Ray ComputedAgedAged, 80 and overEndovascular ProceduresFemaleHumansMaleMiddle AgedPerfusion ImagingRetrospective Studiesacute ischemic strokecomputed tomography perfusionendovascular therapyIntracranial atherosclerotic stenosismechanical thrombectomypredictive model.

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PMID39757633
PMCPMC12246737

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