Evidence map›Paper›PMID 39757623›Full record

SynthesisInfectious disorders drug targets2025

Herbal Medicine for the Management of Wounds: A Systematic Review of Clinical Studies.

Lokman Ali Ahmed, Arshadul Hussain, Pervej Alom Barbhuiya, Samsuj Zaman, Abdul Mannaf Laskar, Manash Pratim Pathak, Partha Pratim Dutta, Saikat Sen

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Infectious disorders drug targets, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. An Update of Phytotherapeutic Advances of Marigold (Plants (Basel, Switzerland) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lokman Ali AhmedFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.
Arshadul HussainFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.
Pervej Alom BarbhuiyaFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.
Samsuj ZamanFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.
Abdul Mannaf LaskarFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.
Manash Pratim PathakFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.ORCID 0000-0002-9182-7948
Partha Pratim DuttaFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.
Saikat SenFaculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati, Assam, PIN-781026, India.ORCID 0000-0002-5279-1532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCuts and wounds are unfortunate yet inevitable events. Traditional remedies have historically harnessed various plants for wound healing, undergoing clinical and pre-clinical scrutiny. Hence, this systematic review focuses on clinically researched herbal formulations for wound healing. METHODOLOGY: Following Preferred Reporting Items for Systematic Reviews and Meta- Analyses (PRISMA) guidelines, databases like Google Scholar, Web of Science, PubMed, Scopus, J-gate, and Ayush Research Portal were meticulously searched for clinical trials involving wound-targeting herbal formulations, alongside a comprehensive hunt for preclinical plant data.

resultsAmong 623 screened documents, 26 published clinical trials spotlighting herbal wound healing formulations were identified. All studies showcased significant wound healing progress, with some surpassing standard betadine treatment. Only one study reported an adverse effect. Within the 26 formulations, 45 distinct plant species were employed, with 35 exhibiting wound healing attributes like antimicrobial, anti-inflammatory, and antioxidant activities scientifically. Enhanced collagen content, stabilized fibers, activated fibroblast cells, increased total protein, elevated growth factors, hydroxyproline, hexosamine, and tissue protein demonstrate the efficacy of plants, such as

conclusionThe findings of the current study indicated that medicinal plants are effective and safe agents for the treatment of wounds, though larger, well-designed trials are needed for definitive role confirmation.

Indexed as

Herbal MedicinePhytotherapyPlant ExtractsPlants, MedicinalWound HealingWounds and InjuriesAnimalsAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsClinical Trials as TopicHumansAnti-Infective AgentsAnti-Inflammatory AgentsAntioxidantsPlant ExtractsCalendula officinalis.clinical trialsHerbal formulationsmedicinal plantpreclinical studywound

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.