Evidence map›Paper›PMID 39757447›Full record

ArticleCNS spectrums2025

Correlation analysis of the platelet-to-lymphocyte ratio with attention-deficit hyperactivity disorder in children aged 6-14: based on the National Health and Nutrition Examination Survey database.

Xianhua Li, Yan Luo, Xiaodan Zeng, Xuewen Qiu, Yang Hua, Lingling Zhan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in CNS spectrums, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xianhua LiPaediatrician, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian, China.
Yan LuoPaediatrician, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian, China.
Xiaodan ZengPaediatrician, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian, China.
Xuewen QiuPaediatrician, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian, China.
Yang HuaPaediatrician, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian, China.
Lingling ZhanPaediatrician, Longyan First Hospital Affiliated to Fujian Medical University, Longyan, Fujian, China.ORCID 0009-0002-8685-2310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to elucidate the association between the platelet-to-lymphocyte ratio (PLR) and the risk of attention deficit hyperactivity disorder (ADHD) in children aged 6-14 based on National Health and Nutrition Examination Survey (NHANES) data.

methodWe utilized data from NHANES 2013-2014 for analysis, with PLR as the independent variable and ADHD as the dependent variable. Weighted logistic regression was used to construct the relationship model. The subgroup analysis with stratification and adjustment for confounding factors was conducted to explore the association between PLR and ADHD risk in children aged 6-14. Finally, the restricted cubic spline (RCS) analysis was carried out to explore the non-linear relationship between PLR and ADHD.

resultsThe study included 1455 samples with 91 ADHD cases. A significant positive association (OR > 1,

conclusionIncreased PLR elevated the risk of ADHD, especially in males, children born to mothers aged 20-29, and children with asthma, with 106.40 possibly being an effective threshold for PLR's impact on ADHD risk.

Indexed as

Attention Deficit Disorder with HyperactivityBlood PlateletsLymphocytesAdolescentChildFemaleHumansMaleNutrition SurveysPlatelet Countattention deficit hyperactivity disorderinflammationNational Health and Nutrition Examination Surveyplatelet-to-lymphocyte ratio

Identifiers

PMID39757447
PMCPMC13064743

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.