Evidence map›Paper›PMID 39757319›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Virtual reality-based Harms tangent screen test for strabismus measurement.

Yaroslava Wenner, Johann Schneider, Timo Drisser, Yu Yi Yang, Thilo Demeter, Maria Fronius, Birgit Lorenz, Thomas Kohnen, Michael Müller, Jochen Triesch

Abstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yaroslava WennerDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany. Yaroslava.Wenner@unimedizin-ffm.de.ORCID http://orcid.org/0000-0002-1914-8174
Johann SchneiderFrankfurt Institute for Advanced Studies (FIAS), Frankfurt am Main, Germany.
Timo DrisserDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Yu Yi YangFrankfurt Institute for Advanced Studies (FIAS), Frankfurt am Main, Germany.
Thilo DemeterDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Maria FroniusDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Birgit LorenzTransMIT Centre of Translational Ophthalmology, c/o Justus-Liebig-University, Giessen, Germany.
Thomas KohnenDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Michael MüllerDepartment of Ophthalmology, Goethe-University, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Jochen TrieschFrankfurt Institute for Advanced Studies (FIAS), Frankfurt am Main, Germany.

Funding

ERA-NET NEURON grant JTC2015German Society for Strabismus, Neuroophthalmology and Pediatric Ophthalmology Research grant 2023Goethe-Universität Frankfurt am Main Digital Clinician Scientist Grant 2023
6 · The paper itself

Abstract

purposeOur study presents a virtual reality-based tangent screen test (VTS) to measure subjective ocular deviations including torsion in nine directions of gaze. The test was compared to the analogous Harms tangent screen test (HTS).

methodsWe used an Oculus Go

resultsWe included 85 patients. Measured horizontal and vertical deviations showed very good agreement between the two methods in all gaze directions (horizontal and vertical ICC: 0.93-0.98). Agreement was lower for torsional deviations (ICC: 0.79-0.93). The mean difference in primary position was 1.5° (95% limits of agreement -3.5° to 6.5°) for horizontal, 0° (-2,7° to 2,7°) for vertical, and 0.3° (-4.0° to 3.0°) for torsional deviations. The average examination time was 6 min with the VTS compared to 15 min with the HTS.

conclusionsVertical and horizontal deviations showed good agreement between both tests measuring a slightly higher esodeviation with VTS probably due to an increased vergence demand. Measurement of torsional misalignment would benefit from a controller with more holding stability, such as a PC-mouse with central wheel, facilitating fine adjustments. VTS allowed automatic documentation, required less time and was easier to use than HTS. KEY MESSAGES: What is known The incidence of neurogenic diplopia increases in the ageing population. The Harms tangent screen test (HTS) reliably measures subjective ocular deviations in patients with diplopia. The HTS requires staff well-trained in orthoptics limiting its use. What is new A novel virtual reality-based tangent screen test (VTS) enables measurement of horizontal, vertical and torsional ocular misalignment and shows a good comparability to the HTS. VTS uses commercially available head-mounted-display and controller, and specifically developed software, requires less time than HTS and allows automatic documentation. VTS administration does not require orthoptic training and can eventually be implemented in a clinical setting to provide a wider availability of subjective squint angle measurements.

Indexed as

Eye MovementsOculomotor MusclesStrabismusVirtual RealityAdultAgedFemaleHumansMaleMiddle AgedReproducibility of ResultsYoung AdultDiplopiaHarms tangent screen testSquint angleStrabismusTorsionVirtual reality

Identifiers

PMID39757319
PMCPMC12149254

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.