Evidence map›Paper›PMID 39757295›Full record

ArticleNPJ digital medicine2025

Efficiency and safety of automated label cleaning on multimodal retinal images.

Tian Lin, Meng Wang, Aidi Lin, Xiaoting Mai, Huiyu Liang, Yih-Chung Tham, Haoyu Chen

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tian Lin *Joint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, 515041, China.ORCID http://orcid.org/0000-0002-6415-5381
Meng Wang *Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0001-7882-1747
Aidi LinJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, 515041, China.
Xiaoting MaiJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, 515041, China.
Huiyu LiangJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, 515041, China.
Yih-Chung ThamCentre for Innovation & Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117549, Singapore.ORCID http://orcid.org/0000-0002-6752-797X
Haoyu ChenJoint Shantou International Eye Center, Shantou University and the Chinese University of Hong Kong, Shantou, Guangdong, 515041, China. drchenhaoyu@gmail.com.ORCID http://orcid.org/0000-0003-0676-4610

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Label noise is a common and important issue that would affect the model's performance in artificial intelligence. This study assessed the effectiveness and potential risks of automated label cleaning using an open-source framework, Cleanlab, in multi-category datasets of fundus photography and optical coherence tomography, with intentionally introduced label noise ranging from 0 to 70%. After six cycles of automatic cleaning, significant improvements are achieved in label accuracies (3.4-62.9%) and dataset quality scores (DQS, 5.1-74.4%). The majority (86.6 to 97.5%) of label errors were accurately modified, with minimal missed (0.5-2.8%) or misclassified (0.4-10.6%). The classification accuracy of RETFound significantly improved by 0.3-52.9% when trained with the datasets after cleaning. We also developed a DQS-guided cleaning strategy to mitigate over-cleaning. Furthermore, external validation on EyePACS and APTOS-2019 datasets boosted label accuracy by 1.3 and 1.8%, respectively. This approach automates label correction, enhances dataset reliability, and strengthens model performance efficiently and safely.

Identifiers

PMID39757295
PMCPMC11701072

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.