Evidence map›Paper›PMID 39757128›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2025

Structures of Gas-Phase Hydrated Phosphotyrosine Revealed by Soft X-ray Action Spectroscopy.

Juliette Leroux, Jean-Yves Chesnel, Carlos Ortiz-Mahecha, Aarathi Nair, Bart Oostenrijk, Laura Pille, Florian Trinter, Lucas Schwob, Sadia Bari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Juliette LerouxCIMAP, CEA/CNRS/ENSICAEN/Université de Caen Normandie, 14050, Caen, France.ORCID https://orcid.org/0009-0004-8057-9231
Jean-Yves ChesnelCIMAP, CEA/CNRS/ENSICAEN/Université de Caen Normandie, 14050, Caen, France.ORCID https://orcid.org/0000-0003-3494-8425
Carlos Ortiz-MahechaHamburg University of Technology, 21073, Hamburg, Germany.ORCID https://orcid.org/0000-0002-1310-5923
Aarathi NairThe Hamburg Centre for Ultrafast Imaging, 22761, Hamburg, Germany.
Bart OostenrijkDeutsches Elektronen-Synchrotron DESY, 22603, Hamburg, Germany.ORCID https://orcid.org/0000-0001-6842-9004
Laura PilleDeutsches Elektronen-Synchrotron DESY, 22603, Hamburg, Germany.ORCID https://orcid.org/0009-0004-5664-7628
Florian TrinterMolecular Physics, Fritz-Haber-Institut der Max-Planck-Gesellschaft, 14195, Berlin, Germany.ORCID https://orcid.org/0000-0002-0891-9180
Lucas SchwobDeutsches Elektronen-Synchrotron DESY, 22603, Hamburg, Germany.ORCID https://orcid.org/0000-0002-4274-365X
Sadia BariDeutsches Elektronen-Synchrotron DESY, 22603, Hamburg, Germany.ORCID https://orcid.org/0000-0003-3985-2051

Funding

Bundesministerium für Bildung und Forschung 13K22CHACentre for molecular water scienceDeutsche Forschungsgemeinschaft 390715994Deutsche Forschungsgemeinschaft 509471550Deutsche Forschungsgemeinschaft HIDSS-0002Emmy Noether programmeHelmholtz Initiative and Networking FundHelmholtz Initiative and Networking Fund.Max-Planck-Gesellschaft MaxWater initiativeRégion Normandie NANOHYDRAD
6 · The paper itself

Abstract

Gas-phase near-edge X-ray absorption mass spectrometry (NEXAMS) was employed at the carbon and oxygen K-edges to probe the influence of a single water molecule on the protonated phosphotyrosine molecule. The results of the photodissociation experiments revealed that the water molecule forms two bonds, with the phosphate group and another chemical group. By comparing the NEXAMS spectra at the carbon and oxygen K-edges with density functional theory calculations, we attributed the electronic transitions responsible for the observed resonances, especially the transitions due to the presence of the water molecule. We showed that the water molecule leads to a specific spectral feature in the partial ion yield of hydrated fragments at 536.4 eV. Moreover, comparing the NEXAMS spectra with the calculated structures allowed us to identify three possible structures for singly hydrated phosphotyrosine that agree with the observed fragmentation and resonances.

Indexed as

BiomoleculesDensity functional theoryNanosolvationSoft X-ray spectroscopy

Identifiers

PMID39757128
PMCPMC11833222

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.