ArticleEnvironmental health and preventive medicine2024
Association of dietary intake of live microbes with bowel health and depression in US adults: a cross-sectional study of NHANES 2005-2010.
Article in Environmental health and preventive medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of fermented foods consumption on gastrointestinal wellbeing in healthy adults: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Association Between Dietary Live Microbes and Diet Quality Among Children and Adults in France.Nutrition bulletin · 2026Article
- Dietary live microorganisms and depression-driven mortality in hypertensive patients: NHANES 2005-2018.Journal of health, population, and nutrition · 2025Article
- Associations of Dietary Live Microbes Intake and Prevalence of Prediabetes in US Adults: A Cross-Sectional Analysis.Journal of multidisciplinary healthcare · 2025Article
- Antidepressant use and all-cause mortality in depressed individuals: A real-world cohort study.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDepression substantially impacts on quality of life, personal relationships, and self-care. Gastrointestinal disorders are the common comorbidity of depression and 24.3% of patients with depression have disordered bowel habits. Dietary intake of live microbes alters the host's microflora and is beneficial for the prevention and control of bowel health and depression. We aim to investigate the association of dietary intake of live microbes with bowel health and depression and to further examine weather bowel health or depression mediates the therapeutic effect of live microbes.
methodsParticipants' data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2005-2010, which is designed to examine the health and nutritional status of the non-institutionalized US population by a complex, multi-stage, probability sampling design. The foods were grouped into categories on the basis of estimated microbial levels: low (<10
resultsA total of 10,785 US adults were selected. The median of MedHi foods intake was 66.1 g/day. Participants in the G2 (OR = 0.739, 95% CI: 0.581-0.941) and G3 (OR = 0.716, 95% CI: 0.585-0.877) groups had significant association with lower risks of depression, and participants in the G3 group had significant association with lower risks of hard stools (OR = 0.885, 95% CI: 0.692-0.989) and loose stools (OR = 0.769, 95% CI: 0.585-0.954). Interestingly, further mediation analyses showed that the association of dietary live microbe intake with depression is mediated by the stool types, and the association of dietary live microbe intake with stool types is mediated by the depression (all P < 0.05).
conclusionsA high dietary intake of live microbes, especially a minimum of 66.1 g of MedHi foods per day, is associated with a lower risk of depression, hard stools, and loose stools consistency. Depression and bowel health mutually act as mediators in this association, indicating dietary intake of live microbes may simultaneously affect bowel health and depression.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.