Evidence map›Paper›PMID 39756816›Full record

ReviewJournal of inherited metabolic disease2025

Biological Basis of Cell Trafficking: A General Overview.

Helena Gimeno-Agud, Yaiza Díaz-Osorio, Alfonso Oyarzábal

Abstract readReview
In one paragraph

Review in Journal of inherited metabolic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Helena Gimeno-AgudDepartment of Neurology and MetabERN; Esplugues de Llobregat, Synaptic Metabolism and Personalized Therapies Lab, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
Yaiza Díaz-OsorioDepartment of Neurology and MetabERN; Esplugues de Llobregat, Synaptic Metabolism and Personalized Therapies Lab, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.
Alfonso OyarzábalDepartment of Neurology and MetabERN; Esplugues de Llobregat, Synaptic Metabolism and Personalized Therapies Lab, Institut de Recerca Sant Joan de Déu, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell trafficking is a tightly regulated biological process for the exchange of signals and metabolites between cell compartments, including four main processes: membrane trafficking (transport of membrane-bound vesicles), autophagy, transport along the cytoskeleton, and membrane contact sites. These processes are cross-sectional to cellular functions, ranging from the transportation of membrane proteins, membranes, and organelles to the elimination of damaged proteins and organelles. In consequence, cell trafficking is crucial for cell survival and homeostasis, serving as a cornerstone for cellular communication and facilitating interactions both with the surrounding environment and between different organelles. Disorders of cell trafficking are clinically and pathophysiological diverse and complex and form the largest group in the recent International Classification of Inherited Metabolic Disorders (ICIMD). In this review, we explore the four categories of cell trafficking and the biological principles that drive these processes. Instead of delving profoundly into each pathway, as comprehensive reviews on those topics already exist, we offer a broad overview of the molecular mechanisms behind cell trafficking, providing a foundational understanding to ease their entry into this subject and enhance comprehension of the other articles featured in this Special Issue.

Indexed as

AutophagyAnimalsBiological TransportCell CommunicationCell MembraneCell MovementCytoskeletonHumansOrganellesProtein Transportautophagycell traffickingcytoskeletonendocytosisexocytosismembrane contact sitesmembrane trafficking

Identifiers

PMID39756816
PMCPMC11700728

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.