ArticlePediatrics2025
A Bundled, Practice-Based Intervention to Increase HPV Vaccination.
Article in Pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Clinician Perceptions of the Impact of Switching HPV Vaccine Initiation to 9-10 Years.Pediatrics · 2026Trial
- A Multicomponent Strategy to Increase Human Papillomavirus Vaccination Rates in Primary Care: A Cluster Randomized Clinical Trial.JAMA network open · 2026Article
- HPV Vaccination in the U.S. Midwest: Barriers and Facilitators of Initiation and Completion in Adolescents and Young Adults.Vaccines · 2025Article
- An Integrated Health System's Approach to Improving Human Papillomavirus Vaccination Rates Through a Systemwide Implementation Strategy.Journal for healthcare quality : official publication of the National Association for Healthcare QualityArticle
- Improving pharmacy-based HPV vaccine delivery through communication training: Findings from a pilot feasibility study.Journal of the American Pharmacists Association : JAPhAArticle
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
BACKGROUND AND
objectivesHuman papillomavirus (HPV) vaccination rates are suboptimal, and missed vaccination opportunities are common. We hypothesized that a bundled intervention improves missed HPV vaccination opportunities.
methodsWe used a pre-post design to assess differences in HPV vaccine missed opportunities (visits when vaccine-eligible adolescents are not vaccinated). We compared rates for a 12-month period before vs those for a 6-month period (February 23, 2022, to August 9, 2022) during a bundled intervention. We implemented the bundled intervention in 24 primary care pediatric practices that had been usual care controls for a prior randomized trial. The bundled intervention involved 3 components: online clinician training on HPV vaccine communication, performance feedback on missed HPV vaccination opportunities, and clinician prompts for HPV vaccination. As a secondary analysis, we compared missed opportunities for these 24 practices vs 48 contemporaneous comparison group practices identified retrospectively.
resultsFor well-child care (WCC) visits, missed HPV vaccination opportunities were improved during vs before the intervention by 4.8 percentage points (95% CI, -7.2% to -2.4%) for initial HPV vaccine doses and a modest 2.2 percentage points (95% CI, -4.4% to -0.0%) for subsequent doses. For other visit types, findings ruled out changes beyond minimal improvements. Missed vaccination opportunity rates for initial HPV vaccination at WCC visits were similar for the 24 intervention practices vs the 48 comparison practices for a 4.5-year period before the intervention, but they improved for intervention practices and worsened for comparison practices during the intervention period (difference, -6.6%; 95% CI, -9.3% to -3.8%).
conclusionsThis bundled intervention appeared to improve HPV vaccination during WCC visits.
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