Evidence map›Paper›PMID 39756433›Full record

ArticleInflammatory bowel diseases2025

Pregnancy With a Stoma is Feasible, Though Associated With Manageable Complications.

Dianne Gelien Bouwknegt, Albertina Henrika Chantall van der Weide, Gerard Dijkstra, Rogier Leon Goetgebuer, Lotte Oldenburg, Willemijn Alexandra van Dop, Meike Madeleine Catherine Hirdes, Jelmer Riemer Prins, Froukje Jantien Hoogenboom, Christien Janneke van der Woude and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Inflammatory bowel diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dianne Gelien BouwknegtDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.ORCID 0000-0002-6208-2967
Albertina Henrika Chantall van der WeideDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.
Gerard DijkstraDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.ORCID 0000-0003-4563-7462
Rogier Leon GoetgebuerDepartment of Gastroenterology and Hepatology, Amsterdam University Medical Center, 1105AZ, Amsterdam, The Netherlands.ORCID 0000-0003-1349-9501
Lotte OldenburgDepartment of Gastroenterology and Hepatology, Amsterdam University Medical Center, 1105AZ, Amsterdam, The Netherlands.ORCID 0000-0002-6086-0964
Willemijn Alexandra van DopDepartment of Gastroenterology and Hepatology, Radboud University Medical Center, 6525GA, Nijmegen, The Netherlands.ORCID 0000-0002-4653-6594
Meike Madeleine Catherine HirdesDepartment of Gastroenterology and Hepatology, University Medical Center Utrecht, 3584CX, Utrecht, The Netherlands.
Jelmer Riemer PrinsDepartment of Obstetrics and Gynaecology, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.ORCID 0000-0002-3984-2163
Froukje Jantien HoogenboomDepartment of Colorectal Surgery, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.
Christien Janneke van der WoudeDepartment of Gastroenterology and Hepatology, Radboud University Medical Center, 6525GA, Nijmegen, The Netherlands.ORCID 0000-0003-3875-6957
Marijn Caroline VisschedijkDepartment of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, 9713GZ, Groningen, The Netherlands.ORCID 0000-0001-7277-7677

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInflammatory bowel disease (IBD) is often diagnosed in young adults, and therefore frequently coincides with pregnancy. Patients may require surgery that includes (temporary) stoma placement. Literature on the occurrence of stoma-complications during pregnancy and the effect on pregnancy outcomes is limited. To evaluate stoma- complications peri- and postpartum, a retrospective study was performed in women who were pregnant while having a stoma.

methodsThis multicentre cohort and survey study included all pregnant patients with IBD and a stoma who delivered between 2016 and 2023 from 5 Dutch university hospitals. Stoma-complications and pregnancy outcomes were retrospectively collected from electronic patient files. A questionnaire assessed patient-reported complications and long-term stoma-related complaints.

resultsIn total, 50 patients were included (median age at conception 31.0 years; 55.2% Crohn's disease and 44.8% ulcerative colitis), comprising 67 pregnancies, 5 of which ended in pregnancy loss. Stoma complications occurred in 44 full-term pregnancies (71.0%), most commonly obstruction (35.5%) and decreased output (29.0%). Surgery was required in four pregnancies due to obstruction (n = 3) and prolapse (n = 2). In the first-year postpartum, 7 patients required surgery for stoma-complications. Amongst 29 women who completed the questionnaire, 10 (34.5%) reported unresolved complications 6 months postpartum. Cesarean sections were performed in 31 (50.0%) pregnancies. Adverse pregnancy outcomes included prematurity (n = 9, 14.5%), low birth weight (n = 9, 14.5%), and dysmaturity (n = 5, 8.1%).

conclusionsPregnancy with a stoma is feasible, though manageable complications often occur. Counseling before pregnancy and close monitoring of symptoms during pregnancy and postpartum are essential for women with IBD and a stoma.

Indexed as

Crohn DiseaseInflammatory Bowel DiseasesPostoperative ComplicationsPregnancy ComplicationsSurgical StomasAdultFeasibility StudiesFemaleFollow-Up StudiesHumansNetherlandsPregnancyPregnancy OutcomeRetrospective StudiesSurveys and QuestionnairesYoung Adultclinical trialsinflammatory bowel diseasepregnancystomasurgery

Identifiers

PMID39756433
PMCPMC12342816

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.