ArticleEuropean journal of applied physiology2025
Vitamin D status and its determinants in German elite athletes.
Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Cholecalciferol and muscle strength in hemodialysis patients: results from the randomized VITADIAL trial.Clinical kidney journal · 2026Article
- The association of VDR gene polymorphisms with serum vitamin D levels and injury predisposition in elite athletes of Kazakhstan.European journal of applied physiology · 2026Article
- Genetic and non-genetic determinants of vitamin D status: a polygenic score analysis in elite athletes.Frontiers in genetics · 2026Article
- FokI Polymorphism of theNutrients · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
purposeThis study investigated elite German athletes to (1) assess their serum 25(OH)D levels and the prevalence of insufficiency, (2) identify key factors influencing serum 25(OH)D levels, and (3) analyze the association between serum 25(OH)D levels and handgrip strength.
methodsIn this cross-sectional study, a total of 474 athletes (231 female), aged 13-39 years (mean 19.3 years), from ten Olympic disciplines were included. Serum 25(OH)D levels were analyzed via liquid chromatography-mass spectrometry, and 17 single nucleotide polymorphisms (SNPs) related to vitamin D metabolism were determined using leukocyte DNA. Grip strength was measured unimanually using a hand-held dynamometer. Multiple linear regressions were used to analyze the influence of SNPs, age, sex, season (summer vs. winter), and discipline (indoor vs. outdoor) on 25(OH)D status. Linear regression analyzed the relationship between handgrip strength and serum 25(OH)D levels.
resultsIn total, 55.5% (n = 263) of athletes demonstrated insufficient serum 25(OH)D levels (< 30 ng/mL, < 75 nmol/L), with 16% (n = 76) showing levels below 20 ng/mL (50 nmol/L). After correction for multiple testing, significant influences on 25(OH)D levels were observed for the C allele of VDBP rs7041 (AC Genotype:
conclusionA high prevalence of insufficient 25(OH)D levels (< 30 ng/mL, < 75 nmol/L) was observed. We identified certain genetic variants as well as age and discipline as predictors of serum 25(OH)D levels. This knowledge may guide individualized diagnostic, nutritional, and supplementation strategies.
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